Affinity DataKi: 2.70nMAssay Description:Inhibition of ERalpha in human MCF7 cellsMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Displacement of [125I]IMPY from human amyloid beta(1-42) aggregates incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition b...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Competitive inhibition of human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH as substrate preincubated for 60 mins followed by substrate addition by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Non-competitive inhibition of electric eel AChE using varying levels of acetylthiocholine iodide as substrate measured at 2 mins interval for 10 mins...More data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of human placental microsome aromatase using [1beta[3H]]androst-4-ene-3,17-dione as substrate after 15 mins in presence of NADPH by liquid...More data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 20 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataKi: 860nMAssay Description:Non-competitive inhibition of equine serum BuChE using varying levels of butyrylthiocholine iodide as substrate measured at 2 mins interval for 10 mi...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Indian Institute of Technology (BHU)
Curated by ChEMBL
Indian Institute of Technology (BHU)
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of ERbeta in human MCF7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate after 15 mins in presence of NADPH by liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.59E+4nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of ERalpha in human MCF7 cells after 36 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0890nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of sulfatase (unknown origin) using 4-MUS as substrateMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]DHEAS as substrate after 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Fluormone-ES2 binding affinity to ERalpha (unknown origin) after 2 hrs by fluorescent polarization based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of ERalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]DHEAS as substrate after 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of sulfatase (unknown origin) expressed in HEK293 cells using [3H]DHEAS as substrate after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH as substrate preincubated for 60 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH as substrate preincubated for 60 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured for ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured for ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of ERalpha (unknown origin) after 18 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
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