Compile Data Set for Download or QSAR
Found 36 with Last Name = 'karig' and Initial = 'g'
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135594((+/-)-2-(6-chloropyridin-3-yl)-9-aza-bicyclo[4.2.1...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135597(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135592(2-(5-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  4.80nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135594((+/-)-2-(6-chloropyridin-3-yl)-9-aza-bicyclo[4.2.1...)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135595(2-(6-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135597(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135595(2-(6-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50115622(2-Pyridazin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)copy SMILEScopy InChI
Affinity DataKi:  68.4nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N530XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50135597(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)copy SMILEScopy InChI
Affinity DataKi:  89nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50110260(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | 2-P...)copy SMILEScopy InChI
Affinity DataKi:  89nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N530XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)copy SMILEScopy InChI
Affinity DataKi:  101nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135593(2-(4-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  234nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135592(2-(5-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  468nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50135593(2-(4-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  927nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50135595(2-(6-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  1.31E+3nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50110259(2-Pyrimidin-5-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)copy SMILEScopy InChI
Affinity DataKi:  1.71E+3nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N530XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135593(2-(4-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  1.99E+3nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50110258((6S)-2-(6-chloropyridin-3-yl)-9-azabicyclo[4.2.1]n...)copy SMILEScopy InChI
Affinity DataKi:  2.76E+3nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N530XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50135594((+/-)-2-(6-chloropyridin-3-yl)-9-aza-bicyclo[4.2.1...)copy SMILEScopy InChI
Affinity DataKi:  2.76E+3nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50110263(2-Pyrazin-2-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)copy SMILEScopy InChI
Affinity DataKi:  5.77E+3nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N530XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50135592(2-(5-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50115624(2-Pyridin-2-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)copy SMILEScopy InChI
Affinity DataKi:  4.75E+4nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N530XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135596(2-(2-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50115623(2-Pyridin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N530XPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50135596(2-(2-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50135596(2-(2-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z31Z26PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171824(US9085572, 34)copy SMILEScopy InChI
Affinity DataIC50: 180nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171821(US9085572, 6)copy SMILEScopy InChI
Affinity DataIC50: 430nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171827(US9085572, 46)copy SMILEScopy InChI
Affinity DataIC50: 700nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171823(US9085572, 26)copy SMILEScopy InChI
Affinity DataIC50: 760nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171822(US9085572, 23)copy SMILEScopy InChI
Affinity DataIC50: 860nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171826(US9085572, 43)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171829(US9085572, 48)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171830(US9085572, 50)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171828(US9085572, 47)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH

US Patent
LigandPNGBDBM171825(US9085572, 35)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70DMQUS Patent