TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 68.4nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 101nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 234nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 468nMAssay Description:Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 927nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 1.31E+3nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 1.71E+3nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: 1.99E+3nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 2.76E+3nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 2.76E+3nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 5.77E+3nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: 4.75E+4nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at rat brain Nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligandMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Bristol
Curated by ChEMBL
University of Bristol
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 using [3H]-nicotine as radioligandMore data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 180nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 430nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 700nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 760nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 860nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.50E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.90E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.90E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 2.20E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 2.30E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
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