Affinity DataKi: 2.18E+4nMAssay Description:Inhibition of Sprague-Dawley rat MGLMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Inhibition of Sprague-Dawley rat MGLMore data for this Ligand-Target Pair
Affinity DataKi: 5.87E+4nMAssay Description:Inhibition of Sprague-Dawley rat MGLMore data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant G6A iPLA2 using arachidonyl-1-14C PAPC and PAPC incubated for 30 mins by HPLC-MS analysis based radioactivity-based g...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant mouse ATX expressed in HEK293 cells using LPC 17:0 as substrate after 30 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant mouse ATX expressed in HEK293 cells using FS3 as substrate preincubated for 15 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant mouse N-terminal polyHis-tagged ATX-beta (Ser49 to Ile862 residues) expressed in HEK293 cells assessed as reduction in clea...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant mouse N-terminal polyHis-tagged ATX-beta (Ser49 to Ile862 residues) expressed in HEK293 cells assessed as reduction in clea...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetPhospholipase A2, membrane associated(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of mouse group 2A secreted phospholipase A2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of ATX in human whole blood assessed as decrease in LPA levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant mouse N-terminal polyHis-tagged ATX-beta (Ser49 to Ile862 residues) expressed in HEK293 cells assessed as reduction in clea...More data for this Ligand-Target Pair
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of human group 2A secreted phospholipase A2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant mouse N-terminal polyHis-tagged ATX-beta (Ser49 to Ile862 residues) expressed in HEK293 cells assessed as reduction in clea...More data for this Ligand-Target Pair
TargetPhospholipase A2, membrane associated(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of mouse group 2A sPLA2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant GIVA cPLA2 in vitro vesicle assayMore data for this Ligand-Target Pair
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human group 2A sPLA2 by fluorescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of human group 5 sPLA2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 445nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant mouse N-terminal polyHis-tagged ATX-beta (Ser49 to Ile862 residues) expressed in HEK293 cells assessed as reduction in clea...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant mouse N-terminal polyHis-tagged ATX-beta (Ser49 to Ile862 residues) expressed in HEK293 cells assessed as reduction in clea...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant GIVA cPLA2 in vitro vesicle assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human group 5 secreted phospholipase A2 by fluorescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human group 5 sPLA2 by fluorescence assayMore data for this Ligand-Target Pair
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human group 2A sPLA2 by fluorescence assayMore data for this Ligand-Target Pair
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human group 2A sPLA2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human group 5 sPLA2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human group 5 sPLA2 by fluorescence assayMore data for this Ligand-Target Pair
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