Compile Data Set for Download or QSAR
Found 184 with Last Name = 'manfroni' and Initial = 'g'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50313107(4-chloro-N-cyclopropyl-3-(1-(2,6-difluorophenyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50314780(CHEMBL1091199 | N-Cyclopropyl-3-(1-(2,4-difluoroph...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50002338((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-Raclopride from human D2 receptor (unknown origin) expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMedDrugBank
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50418613(CHEMBL1232887)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50265033(CHEMBL522579 | N-cyclopropyl-2',6-dimethyl-4'-(5-m...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263093(6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopr...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50002338((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)copy SMILEScopy InChI
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))TBA
LigandPNGBDBM50002338((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)copy SMILEScopy InChI
Affinity DataKi:  84nMAssay Description:Displacement of [3H]-Ketanserin from human 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50002338((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)copy SMILEScopy InChI
Affinity DataKi:  181nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50565002(CHEMBL4778666)copy SMILES
Affinity DataKi:  222nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM25980(BMCL18324 Compound 3 | CHEMBL270164 | N-(3-cyanoph...)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKi:  252nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as free enzyme after 1 hr in presence of ss-RNA P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50565002(CHEMBL4778666)copy SMILES
Affinity DataKi:  367nMAssay Description:Displacement of [3H]-Raclopride from human D2 receptor (unknown origin) expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50565001(CHEMBL4797066)copy SMILES
Affinity DataKi:  387nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM25981(BMCL18324 Compound 17 | CHEMBL273158 | D3RKN_78 | ...)copy SMILEScopy InChI
Affinity DataKi:  480nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50565001(CHEMBL4797066)copy SMILES
Affinity DataKi:  639nMAssay Description:Displacement of [3H]-Raclopride from human D2 receptor (unknown origin) expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50565000(CHEMBL4791959)copy SMILES
Affinity DataKi:  688nMAssay Description:Displacement of [3H]-Raclopride from human D2 receptor (unknown origin) expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50565000(CHEMBL4791959)copy SMILES
Affinity DataKi:  758nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50565001(CHEMBL4797066)copy SMILES
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))TBA
LigandPNGBDBM50565001(CHEMBL4797066)copy SMILES
Affinity DataKi:  1.24E+3nMAssay Description:Displacement of [3H]-Ketanserin from human 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKi:  1.54E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as free enzyme after 1 hr in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKi:  1.58E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as enzyme-substrate complex after 1 hr in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))TBA
LigandPNGBDBM50565000(CHEMBL4791959)copy SMILES
Affinity DataKi:  1.75E+3nMAssay Description:Displacement of [3H]-Ketanserin from human 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))TBA
LigandPNGBDBM50565002(CHEMBL4778666)copy SMILES
Affinity DataKi:  1.76E+3nMAssay Description:Displacement of [3H]-Ketanserin from human 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50565000(CHEMBL4791959)copy SMILES
Affinity DataKi:  2.15E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50565002(CHEMBL4778666)copy SMILES
Affinity DataKi:  2.34E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73JGDPubMed
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)copy SMILEScopy InChI
Affinity DataKi:  4.33E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as enzyme-substrate complex after 1 hr in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50252739(CHEMBL494072 | N-Cyclopropyl-4-methyl-3-(2-((2-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50509054(CHEMBL1232751)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50494296(CHEMBL3086685)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50509055(CHEMBL4575052)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50348310(CHEMBL1800911 | US8772288, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50313107(4-chloro-N-cyclopropyl-3-(1-(2,6-difluorophenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM20657(4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-m...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50331625(5-amino-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphen...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM20649(N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50296645(CHEMBL559401 | N-cyclopropyl-3-(1-(2,4-difluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50236473((R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50327020(4-(5-(Isoxazol-3-ylcarbamoyl)-2-methylphenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50509059(CHEMBL4593539)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38WW2PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50492393(CHEMBL2401978)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50509053(CHEMBL4535046)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38WW2PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50327009(4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetGenome polyprotein(Dengue virus)
Universit£ degli Studi di Perugia

Curated by ChEMBL
LigandPNGBDBM50464490(CHEMBL4282493)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of DENV3 full length NS5 RdRp assessed as decrease in dsRNA levels preincubated for 20 mins followed by ss-RNA and ATTO-CTP, ATP, GTP and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39GTPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50058303(BILR 355 | CHEMBL1630842)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of HIV reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1TDBPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50398148(CHEMBL2177219)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)copy SMILES
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged P38 alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38WW2PubMed
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