Compile Data Set for Download or QSAR
Found 300 with Last Name = 'martelli' and Initial = 'g'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)copy SMILEScopy InChI
Affinity DataKi:  10.2nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50143282((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321015(4-Methyl-3-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dode...)copy SMILEScopy InChI
Affinity DataKi:  9.50E+3nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321023((-)-Norferruginine | CHEMBL1164304)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321018(CHEMBL1163516 | and 5-bromo-3-oxa-4,11-diazatricyc...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321020(5-Methoxy-3-oxa-4,11-diazatricyclo[6.2.1.0'2,6]und...)copy SMILEScopy InChI
Affinity DataKi:  2.82E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321013(3-bromo-5-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dodec...)copy SMILEScopy InChI
Affinity DataKi:  2.85E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321019(3-Methoxy-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]und...)copy SMILEScopy InChI
Affinity DataKi:  6.80E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321021(4-Methyl-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]unde...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321022(4-Methyl-3-oxa-4,11-diazatricyclo[6.2.1.0'2,6]unde...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321016(4-Methyl-5-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dode...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50321017(3-Bromo-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]undec...)copy SMILEScopy InChI
Affinity DataKi:  1.09E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50378786(CHEMBL1794974)copy SMILEScopy InChI
Affinity DataKi:  1.70E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08XDPubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))TBA
LigandPNGBDBM50550223(CHEMBL4794300)copy SMILES
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50439683(CHEMBL2418221)copy SMILEScopy InChI
Affinity DataIC50: 0.670nMAssay Description:Antagonist activity at alpha5beta1 in human K562 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibrone...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))TBA
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 0.840nMAssay Description:Antagonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505781(CHEMBL4461668)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50021394(CHEMBL3289605)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505781(CHEMBL4461668)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as inhibition of VCAM1-induced cell adhesion pre-incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505781(CHEMBL4461668)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))TBA
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50505776(CHEMBL4454796)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Binding affinity to alphaVbeta3 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))TBA
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550224(CHEMBL4797755)copy SMILES
Affinity DataIC50: 5.5nMAssay Description:Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50004058((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Inhibition of fibrinogen binding to alpha2bbeta3 isolated from human HEL cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550222(CHEMBL4777693)copy SMILES
Affinity DataIC50: 7.60nMAssay Description:Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550222(CHEMBL4777693)copy SMILES
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50004058((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at alpha2bbeta3 in human HEL cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50505774(CHEMBL4469125)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Binding affinity to alphaVbeta3 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550223(CHEMBL4794300)copy SMILES
Affinity DataIC50: 9.70nMAssay Description:Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505772(CHEMBL4589062)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50550223(CHEMBL4794300)copy SMILES
Affinity DataIC50: 9.90nMAssay Description:Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550225(CHEMBL4764510)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505773(CHEMBL4593469)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Binding affinity to alpha5beta1 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))TBA
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))TBA
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550225(CHEMBL4764510)copy SMILES
Affinity DataIC50: 17nMAssay Description:Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505775(CHEMBL4442651)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Binding affinity to alpha4beta1 integrin receptor (unknown origin) incubated for 1 hr by scintillation proximity binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))TBA
LigandPNGBDBM50550225(CHEMBL4764510)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of fibronectin binding to alphaVbeta6 isolated form human HT-29 cells incubated for 1 hr by scintillation-proximity assay based competitiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50222360(Ac-Asp-Arg-Leu-Asp-Ser-OH | CHEMBL238484)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50505770(CHEMBL4446073)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Binding affinity to alphaVbeta3 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))TBA
LigandPNGBDBM50439683(CHEMBL2418221)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550225(CHEMBL4764510)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as reduction in fibronectin-induced cell adhesion pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
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