Compile Data Set for Download or QSAR
Found 78 with Last Name = 'packham' and Initial = 'g'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346586(CHEMBL1795981 | US8765820, 5a)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346585(CHEMBL1795980 | S2101)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346584(CHEMBL1795979)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346589(CHEMBL1795974 | CHEMBL255520)copy SMILEScopy InChI
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346583(CHEMBL1795978)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346591(CHEMBL1795982)copy SMILEScopy InChI
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346582(CHEMBL1795977)copy SMILEScopy InChI
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346590(CHEMBL1795975)copy SMILEScopy InChI
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346594(CHEMBL1795976)copy SMILEScopy InChI
Affinity DataKi:  1.17E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)copy SMILEScopy InChI
Affinity DataKi:  2.66E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)copy SMILEScopy InChI
Affinity DataKi:  2.81E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346587(CHEMBL1795972)copy SMILEScopy InChI
Affinity DataKi:  4.18E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346588(CHEMBL1795973)copy SMILEScopy InChI
Affinity DataKi:  7.96E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346592(CHEMBL1795983)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50346593(CHEMBL1795984)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)copy SMILEScopy InChI
Affinity DataKi:  1.68E+5nMAssay Description:Inhibition of human truncated LSD1 lacking N-terminal 184 amino acidsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)copy SMILEScopy InChI
Affinity DataKi:  1.68E+5nMAssay Description:Inhibition of human truncated LSD1 lacking N-terminal 184 amino acidsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SWTPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19153((1S,7R,10S,16E,21R)-7,21-bis(propan-2-yl)-2-oxa-12...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19152((1S,7R,10S,16E,21R)-21-methyl-7-(propan-2-yl)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)copy SMILEScopy InChI
Affinity DataIC50: 3.97nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM136702(US8865655, 10)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z036V4US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19154((6R,9R,12R,16R)-9,12-dimethyl-6-(propan-2-yl)-16-[...)copy SMILEScopy InChI
Affinity DataIC50: 17.5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM136703(US8865655, 11)copy SMILEScopy InChI
Affinity DataIC50: 21.6nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z036V4US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM136704(US8865655, 16)copy SMILEScopy InChI
Affinity DataIC50: 47nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z036V4US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19155((6R,9S,12R,16R)-16-[(1E)-4-(acetylsulfanyl)but-1-e...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172493((13S)-3-hydroxy-16-(hydroxymethylene)-13-methyl-7,...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM136705(US8865655, 17)copy SMILEScopy InChI
Affinity DataIC50: 126nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z036V4US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172503((S)-6a-Methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahyd...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 196nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172504((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50366344(CHEMBL1627450)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172495((S)-8-(2-Methoxy-ethyl)-6a-methyl-4b,5,6,6a,8,10,1...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172499(3-((S)-2-Hydroxy-6a-methyl-4b,6,6a,10,10a,10b,11,1...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 775nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172496((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)copy SMILEScopy InChI
Affinity DataIC50: 787nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50256990(CHEMBL4063580)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human His-tagged LSD1 expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1562PPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172500((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19152((1S,7R,10S,16E,21R)-21-methyl-7-(propan-2-yl)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 881nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19153((1S,7R,10S,16E,21R)-7,21-bis(propan-2-yl)-2-oxa-12...)copy SMILEScopy InChI
Affinity DataIC50: 897nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172494(((S)-2-Hydroxy-6a-methyl-4b,6,6a,10,10a,10b,11,12-...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172502((S)-9-Hydroxymethyl-6a-methyl-4b,5,6,6a,8,10,10a,1...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370664(CHEMBL1627756)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50256943(CHEMBL4088366)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human His-tagged LSD1 expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1562PPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172491((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50261813(CHEMBL468597 | trans-2-(para-trifluoromethylphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human His-tagged LSD1 expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1562PPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172497((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172501((S)-6a,8-Dimethyl-4b,5,6,6a,8,10,10a,10b,11,12-dec...)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
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