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Found 208 with Last Name = 'trani' and Initial = 'g'
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037076(CHEMBL3355737)copy SMILES
Affinity DataKi:  0.170nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037066(CHEMBL3355728)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037077(CHEMBL3355738)copy SMILES
Affinity DataKi:  0.380nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443182(CHEMBL3086538)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443181(CHEMBL3086535)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443180(CHEMBL3086536)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037070(CHEMBL3355732)copy SMILES
Affinity DataKi:  1.20nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415362(CHEMBL601857)copy SMILEScopy InChI
Affinity DataKi:  1.58nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037074(CHEMBL3355736)copy SMILES
Affinity DataKi:  1.60nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037071(CHEMBL3355733)copy SMILES
Affinity DataKi:  1.80nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443178(CHEMBL3086537)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037068(CHEMBL3355730)copy SMILES
Affinity DataKi:  2.30nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443177(CHEMBL3086533)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415354(CHEMBL600836)copy SMILEScopy InChI
Affinity DataKi:  2.51nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415365(CHEMBL609757)copy SMILEScopy InChI
Affinity DataKi:  2.51nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415360(CHEMBL610062)copy SMILEScopy InChI
Affinity DataKi:  3.16nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415361(CHEMBL592649)copy SMILEScopy InChI
Affinity DataKi:  3.98nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415352(CHEMBL600636)copy SMILEScopy InChI
Affinity DataKi:  3.98nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415359(CHEMBL601854)copy SMILEScopy InChI
Affinity DataKi:  3.98nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037063(CHEMBL3355726)copy SMILES
Affinity DataKi:  4nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50442147(CHEMBL2441269)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415363(CHEMBL605579)copy SMILEScopy InChI
Affinity DataKi:  5.01nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415358(CHEMBL601639)copy SMILEScopy InChI
Affinity DataKi:  5.01nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443189(CHEMBL3086327)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037069(CHEMBL3355731)copy SMILES
Affinity DataKi:  5.30nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415356(CHEMBL609472)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415355(CHEMBL600837)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443188(CHEMBL3086329)copy SMILEScopy InChI
Affinity DataKi:  6.40nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443187(CHEMBL3086328)copy SMILEScopy InChI
Affinity DataKi:  6.60nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415353(CHEMBL604949)copy SMILEScopy InChI
Affinity DataKi:  7.94nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037067(CHEMBL3355729)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443175(CHEMBL3086534)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415351(CHEMBL601246)copy SMILEScopy InChI
Affinity DataKi:  12.6nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415364(CHEMBL602475)copy SMILEScopy InChI
Affinity DataKi:  12.6nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037065(CHEMBL3355727)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415346(CHEMBL602085)copy SMILEScopy InChI
Affinity DataKi:  15.8nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415364(CHEMBL602475)copy SMILEScopy InChI
Affinity DataKi:  15.8nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415360(CHEMBL610062)copy SMILEScopy InChI
Affinity DataKi:  15.8nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415359(CHEMBL601854)copy SMILEScopy InChI
Affinity DataKi:  19.9nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037072(CHEMBL3355734)copy SMILES
Affinity DataKi:  20nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415350(CHEMBL601034)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415358(CHEMBL601639)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415366(CHEMBL601455)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415348(CHEMBL602086)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443186(CHEMBL3086331)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443185(CHEMBL3086330)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50443184(CHEMBL3086544)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415349(CHEMBL601033)copy SMILEScopy InChI
Affinity DataKi:  50.1nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415363(CHEMBL605579)copy SMILEScopy InChI
Affinity DataKi:  50.1nMAssay Description:Antagonist activity at human recombinant CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-stimulated increase of intracellular ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JG4PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec UK Ltd

Curated by ChEMBL
LigandPNGBDBM50037060(CHEMBL3355311)copy SMILES
Affinity DataKi:  53nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
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