Found 259 with Last Name = 'vassiliou' and Initial = 'g' TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged P300 measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged P300 measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of CBP in human PBMC derived naive CD4-positive T cells assessed as decrease in FOXP3 mRNA level in Treg cells measured after 4 days by qu...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type B-raf in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human TDO2 assessed as decrease in conversion of L-tryptophan to N-formylkynurenine preincubated for 5 mins followed by 0.2...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human TDO2 assessed as decrease in conversion of L-tryptophan to N-formylkynurenine preincubated for 5 mins followed by 0.2...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
