Found 220 with Last Name = 'de boer' and Initial = 'g' 
Affinity DataKi: 370nMAssay Description:Displacement of [3H]BNZA from Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.02E+3nMAssay Description:Displacement of [3H]BNZA from Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human Nav1.2 by V1/2 protocol based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells assessed as inhibition of late channel current at holding potential of -95 mVMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells assessed as inhibition of peak channel current at holding potential of -95 mVMore data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human Nav1.5 by automated voltage clamp electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of human Nav1.5 by automated voltage clamp electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by sodium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human Nav1.5 by automated voltage clamp electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human Nav1.5 by automated voltage clamp electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human Nav1.1 by V1/2 protocol based analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells by sodium influx assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human Nav1.6 by V1/2 protocol based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human Nav1.5 by V1/2 protocol based analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Homo sapiens (Human))
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Xenon Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
