Compile Data Set for Download or QSAR
Found 928 with Last Name = 'look' and Initial = 'gc'
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM532343(US11214540, Example 1)copy SMILES
Affinity DataKi:  0.200nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532348(US11214540, Example 6)copy SMILES
Affinity DataKi:  0.300nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532350(US11214540, Example 8)copy SMILES
Affinity DataKi:  0.400nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM349368(US10207991, Ex. Cpd. No. 11 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.440nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13641
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349368(US10207991, Ex. Cpd. No. 11 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6W8RUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349368(US10207991, Ex. Cpd. No. 11 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:Binding affinity to Sigma 2-receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21Q9PubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349368(US10207991, Ex. Cpd. No. 11 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92DFNUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349368(US10207991, Ex. Cpd. No. 11 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JRGUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532346(US11214540, Example 4)copy SMILES
Affinity DataKi:  0.5nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349518(US10207991, Ex. Cpd. No. 34 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JRGUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM349518(US10207991, Ex. Cpd. No. 34 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13641
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349518(US10207991, Ex. Cpd. No. 34 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92DFNUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349518(US10207991, Ex. Cpd. No. 34 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6W8RUS Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349505(US10207991, Ex. Cpd. No. 20 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.570nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92DFNUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM349505(US10207991, Ex. Cpd. No. 20 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.570nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13641
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349505(US10207991, Ex. Cpd. No. 20 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.570nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JRGUS Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349505(US10207991, Ex. Cpd. No. 20 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.570nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6W8RUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM532344(US11214540, Example 2)copy SMILES
Affinity DataKi:  0.600nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349505(US10207991, Ex. Cpd. No. 20 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.670nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92DFNUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349505(US10207991, Ex. Cpd. No. 20 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.670nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JRGUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM349505(US10207991, Ex. Cpd. No. 20 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.670nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13641
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349505(US10207991, Ex. Cpd. No. 20 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  0.670nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6W8RUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532349(US11214540, Example 7)copy SMILES
Affinity DataKi:  0.700nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532343(US11214540, Example 1)copy SMILES
Affinity DataKi:  0.700nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532352(US11214540, Example 10)copy SMILES
Affinity DataKi:  0.700nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM532345(US11214540, Example 3)copy SMILES
Affinity DataKi:  0.760nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM532347(US11214540, Example 5)copy SMILES
Affinity DataKi:  0.800nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM532346(US11214540, Example 4)copy SMILES
Affinity DataKi:  0.800nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532358(US11214540, Example 16)copy SMILES
Affinity DataKi:  0.800nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532344(US11214540, Example 2)copy SMILES
Affinity DataKi:  0.900nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532364(US11214540, Example 22)copy SMILES
Affinity DataKi:  1nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532362(US11214540, Example 20)copy SMILES
Affinity DataKi:  1nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532355(US11214540, Example 13)copy SMILES
Affinity DataKi:  1nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532354(US11214540, Example 12)copy SMILES
Affinity DataKi:  1nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM532348(US11214540, Example 6)copy SMILES
Affinity DataKi:  1nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM349569(US10207991, Ex. Cpd. No. 87 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13641
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349569(US10207991, Ex. Cpd. No. 87 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JRGUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349569(US10207991, Ex. Cpd. No. 87 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92DFNUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349569(US10207991, Ex. Cpd. No. 87 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6W8RUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM349570(US10207991, Ex. Cpd. No. 88 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13641
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM532359(US11214540, Example 17)copy SMILES
Affinity DataKi:  1.30nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61PFRUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349570(US10207991, Ex. Cpd. No. 88 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6W8RUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349570(US10207991, Ex. Cpd. No. 88 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92DFNUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349570(US10207991, Ex. Cpd. No. 88 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JRGUS Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349578(US10207991, Ex. Cpd. No. 103 | US10611728, Example...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6W8RUS Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349365(US10207991, Ex. Cpd. No. 10 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6W8RUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM349578(US10207991, Ex. Cpd. No. 103 | US10611728, Example...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13641
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM349365(US10207991, Ex. Cpd. No. 10 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13641
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349365(US10207991, Ex. Cpd. No. 10 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JRGUS Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.

US Patent
LigandPNGBDBM349365(US10207991, Ex. Cpd. No. 10 | US10611728, Example ...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92DFNUS Patent
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