Compile Data Set for Download or QSAR
Found 93 with Last Name = 'smith' and Initial = 'gj'
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291312(4-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50075719(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291315(5-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291311(6-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291316(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075719(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Tested for its inhibitory activity against human microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291317(CHEMBL154472 | [3-Allyl-4-(3-hydroxy-1-aza-bicyclo...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291318(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi: >250nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291313(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi: >250nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291319(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi: >250nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50291314(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataKi: >250nMAssay Description:Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WFT
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052343(3-Biphenyl-4-ylethynyl-1-aza-bicyclo[2.2.2]octan-3...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052350(3-((E)-2-Biphenyl-4-yl-vinyl)-1-aza-bicyclo[2.2.2]...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052342(3-(2-Biphenyl-4-yl-ethyl)-1-aza-bicyclo[2.2.2]octa...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052353(3-(4-Benzothiazol-2-yl-phenyl)-1-aza-bicyclo[2.2.2...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50075719(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Compound was measured for the inhibition of rat microsomal squalene synthase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85TQPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052355(3-(2-Biphenyl-4-yl-ethyl)-1-aza-bicyclo[2.2.2]octa...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052377(3-(Biphenyl-4-ylsulfanylmethyl)-1-aza-bicyclo[2.2....)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetDiacylglycerol O-acyltransferase 1(Rattus norvegicus (rat))
AstraZeneca

LigandPNGBDBM27950(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014VRPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052376(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octane | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052358(3-(Biphenyl-4-yloxymethyl)-1-aza-bicyclo[2.2.2]oct...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM27950(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014VRPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Compound was measured for the inhibition of rat microsomal squalene synthase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85TQPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052366(3-(4'-Fluoro-biphenyl-4-yl)-1-aza-bicyclo[2.2.2]oc...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052352(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]oct-2-ene | CH...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetDiacylglycerol O-acyltransferase 1(Rattus norvegicus (rat))
AstraZeneca

LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014VRPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052367(3-(Biphenyl-4-ylsulfanyl)-1-aza-bicyclo[2.2.2]octa...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052357(3-Biphenyl-4-ylmethyl-1-aza-bicyclo[2.2.2]octane |...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM27951(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014VRPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM27949(4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014VRPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052372(3-(4-Thiazol-2-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052341(3-(4-Pyrimidin-2-yl-phenyl)-1-aza-bicyclo[2.2.2]oc...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetLanosterol synthase(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50095601(CHEMBL25405 | [4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7GX6PubMed
TargetLanosterol synthase(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50095598(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7GX6PubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052364(3-(4-Thiophen-2-yl-phenyl)-1-aza-bicyclo[2.2.2]oct...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetLanosterol synthase(Rattus norvegicus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50095601(CHEMBL25405 | [4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:In vitro percent inhibitory activityof the compound against rat microsomal OSC enzyme at 1 microM concentrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7GX6PubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052373(3-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylo...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052344(3-Biphenyl-3-yl-1-aza-bicyclo[2.2.2]octan-3-ol | C...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052362(3-(2-Phenyl-thiazol-5-yl)-1-aza-bicyclo[2.2.2]octa...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM27952(2-[5-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)copy SMILEScopy InChI
Affinity DataIC50: 69nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014VRPubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50052361(3-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylo...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D7GPubMed
TargetLanosterol synthase(Rattus norvegicus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50095600(CHEMBL148268 | [4-(4-Iodo-benzenesulfonyl)-piperaz...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:In vitro inhibitory activityof the compound against rat microsomal 2,3-Oxidosqualene cyclase-Lanosterol synthase (OSC)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7GX6PubMed
TargetLanosterol synthase(Rattus norvegicus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50095599(CHEMBL25285 | {4-[4-(4,5-Dihydro-oxazol-2-yl)-benz...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activityof the compound against rat microsomal 2,3-Oxidosqualene lanosterol cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7GX6PubMed
TargetLanosterol synthase(Rattus norvegicus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of compound was measured on rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85TQPubMed
TargetLanosterol synthase(Rattus norvegicus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50075719(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of compound was measured on rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85TQPubMed
TargetLanosterol synthase(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50095597(CHEMBL359233 | [4-(4-Bromo-benzenesulfonyl)-pipera...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7GX6PubMed
TargetLanosterol synthase(Rattus norvegicus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50095598(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Compound was tested for its inhibition against rat OSC enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7GX6PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM27953(2-[3-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014VRPubMed
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