Compile Data Set for Download or QSAR
Found 12 with Last Name = 'cragg' and Initial = 'gm'
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S52PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
NIH Special Volunteer

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal his-tagged BRAF V600E mutant (448 to 723 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed a...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50469586(1,3,4,5 Tetra-O-Galloylquinic Acid | CHEMBL36985)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S52PubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50480331(CHEMBL498876)copy SMILEScopy InChI
Affinity DataIC50: 946nMAssay Description:Inhibition of HIV1 integrase-catalyzed disintegration activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S52PubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50362839(CHEMBL249447)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of HIV1 integrase-catalyzed disintegration activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S52PubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Tested for 50 % inhibition of tubulin polymerization by turbidimetric assayMore data for this Ligand-Target Pair
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50064891(5,7,3'-trihydroxy-3,6-4'-trimethoxyflavone | 5,7-D...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for 50 % inhibition of tubulin polymerization by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N91
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S52PubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S52PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50478416(CHEBI:65536 | CHEMBL444821)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S52PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50478415(Buchapine | CHEBI:65535)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S52PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
NIH Special Volunteer

Curated by ChEMBL
LigandPNGBDBM50172099(CHEMBL1231605)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal his-tagged BRAF V600E mutant (448 to 723 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37Z73PubMed