Compile Data Set for Download or QSAR
Found 35 with Last Name = 'textor' and Initial = 'gs'
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31587(oxadiazole derivative, 20x)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31586(oxadiazole derivative, 20w)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31578(oxadiazole derivative, 20o)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31584(oxadiazole derivative, 20u)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31577(oxadiazole derivative, 20n)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31572(oxadiazole derivative, 20m)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31580(oxadiazole derivative, 20q)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31583(oxadiazole derivative, 20t)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31585(oxadiazole derivative, 20v)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31588(oxadiazole derivative, 20y)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31570(oxadiazole derivative, 20k)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31579(oxadiazole derivative, 20p)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31581(oxadiazole derivative, 20r)copy SMILEScopy InChI
Affinity DataIC50: 18nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31582(oxadiazole derivative, 20s)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31571(oxadiazole derivative, 20l)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31560(oxadiazole derivative, 20j)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31562(oxadiazole derivative, 20b)copy SMILEScopy InChI
Affinity DataIC50: 54nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31559(oxadiazole derivative, 1)copy SMILEScopy InChI
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31568(oxadiazole derivative, 20i)copy SMILEScopy InChI
Affinity DataIC50: 68nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31567(oxadiazole derivative, 20g)copy SMILEScopy InChI
Affinity DataIC50: 91nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31564(oxadiazole derivative, 20e)copy SMILEScopy InChI
Affinity DataIC50: 94nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31565(oxadiazole derivative, 20d)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31561(oxadiazole derivative, 20a)copy SMILEScopy InChI
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31563(oxadiazole derivative, 20c)copy SMILEScopy InChI
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31566(oxadiazole derivative, 20f)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31574(oxadiazole derivative, 23)copy SMILEScopy InChI
Affinity DataIC50: 330nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31573(oxadiazole derivative, 21)copy SMILEScopy InChI
Affinity DataIC50: 340nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31569(oxadiazole derivative, 20h)copy SMILEScopy InChI
Affinity DataIC50: 630nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31576(oxadiazole derivative, 28)copy SMILEScopy InChI
Affinity DataIC50: 680nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetProtein kinase C theta type(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31587(oxadiazole derivative, 20x)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Assays for serine/threonine kinases using radiolabeled [gamma-33P] ATP (GE Healthcare, Piscataway, NJ) were performed in 96 well plates. Prior to the...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31587(oxadiazole derivative, 20x)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Assays for serine/threonine kinases using radiolabeled [gamma-33P] ATP (GE Healthcare, Piscataway, NJ) were performed in 96 well plates. Prior to the...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetMitogen-activated protein kinase kinase kinase 1(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31587(oxadiazole derivative, 20x)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Assays for serine/threonine kinases using radiolabeled [gamma-33P] ATP (GE Healthcare, Piscataway, NJ) were performed in 96 well plates. Prior to the...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31575(oxadiazole derivative, 26)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31587(oxadiazole derivative, 20x)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Assays for serine/threonine kinases using radiolabeled [gamma-33P] ATP (GE Healthcare, Piscataway, NJ) were performed in 96 well plates. Prior to the...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31587(oxadiazole derivative, 20x)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Human p35/ cyclin dependent kinase 5 (CDK5) was purchased from Millipore Corp. (Bedford, MA), which was expressed as N-terminal GST fusion protein us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed