Compile Data Set for Download or QSAR
Found 71 with Last Name = 'balogh' and Initial = 'gt'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)copy SMILEScopy InChI
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]R21412 from recombinant human mGluR5a expressed in human A18 cell membrane homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236748(CHEMBL4081358)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]R21412 from from in Sprague-Dawley rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236745(CHEMBL4097994)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236742(CHEMBL4098854)copy SMILEScopy InChI
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236711(CHEMBL4096394)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139453(CHEMBL3763653)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139450(CHEMBL3764138)copy SMILEScopy InChI
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)copy SMILEScopy InChI
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [3H]R21412 from mGluR5 in male human post mortem parietal cortical tissue after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236751(CHEMBL4091111)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139452(CHEMBL3764943)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [3H]R21412 from mGluR5 in female human post mortem parietal cortical tissue after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236752(CHEMBL4068928)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236744(CHEMBL4092590)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236709(CHEMBL4082155)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139450(CHEMBL3764138)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236750(CHEMBL4070152)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236712(CHEMBL4069140)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236753(CHEMBL4090008)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236749(CHEMBL4080811)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236713(CHEMBL4088680)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236743(CHEMBL4100326)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139451(CHEMBL3765747)copy SMILEScopy InChI
Affinity DataKi:  52nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139451(CHEMBL3765747)copy SMILEScopy InChI
Affinity DataKi:  68nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236710(CHEMBL4071804)copy SMILEScopy InChI
Affinity DataKi:  71nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236746(CHEMBL4063183)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236747(CHEMBL4082312)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236752(CHEMBL4068928)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139453(CHEMBL3763653)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Negative allosteric modulation of mGluR5 in E17 Sprague-Dawley rat primary neuronal cultures assessed as reduction of DHPG-induced cytosolic Ca2+ inf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236745(CHEMBL4097994)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236748(CHEMBL4081358)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236709(CHEMBL4082155)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139452(CHEMBL3764943)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236742(CHEMBL4098854)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236750(CHEMBL4070152)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50170230(CHEMBL445990)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human DAAO using D-KYN as substrate preincubated for 20 mins followed by substrate addition measured after 30 mins by FP-6300-based flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ359VPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236711(CHEMBL4096394)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Binding affinity towards Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236751(CHEMBL4091111)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236712(CHEMBL4069140)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236749(CHEMBL4080811)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236713(CHEMBL4088680)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236753(CHEMBL4090008)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50460191(CHEMBL4225929)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human DAAO using D-KYN as substrate preincubated for 20 mins followed by substrate addition measured after 30 mins by FP-6300-based flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ359VPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)copy SMILEScopy InChI
Affinity DataIC50: 133nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50460192(CHEMBL4224785)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human DAAO using D-KYN as substrate preincubated for 20 mins followed by substrate addition measured after 30 mins by FP-6300-based flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ359VPubMed
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