Compile Data Set for Download or QSAR
Found 40 with Last Name = 'akita' and Initial = 'h'
TargetATP-binding cassette sub-family C member 3(Rattus norvegicus)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391002(CHEMBL2074599)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44RCWPubMed
TargetABC-type glutathione-S-conjugate transporter(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391002(CHEMBL2074599)copy SMILEScopy InChI
Affinity DataKi:  5.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44RCWPubMed
TargetATP-binding cassette sub-family C member 3(Rattus norvegicus)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391003(CHEMBL493586)copy SMILEScopy InChI
Affinity DataKi:  7.70E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from Mrp3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44RCWPubMed
TargetATP-binding cassette sub-family C member 3(Rattus norvegicus)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391004(CHEMBL213947)copy SMILEScopy InChI
Affinity DataKi:  8.38E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from Mrp3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44RCWPubMed
TargetATP-binding cassette sub-family C member 3(Rattus norvegicus)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataKi:  9.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from Mrp3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44RCWPubMed
TargetABC-type glutathione-S-conjugate transporter(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391003(CHEMBL493586)copy SMILEScopy InChI
Affinity DataKi:  1.05E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44RCWPubMed
TargetABC-type glutathione-S-conjugate transporter(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391004(CHEMBL213947)copy SMILEScopy InChI
Affinity DataKi:  3.37E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44RCWPubMed
TargetABC-type glutathione-S-conjugate transporter(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+6nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44RCWPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274048(CHEMBL489866 | N-[(5R,6R)-17-(Cyclopropylmethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.0190nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274519((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.0350nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274401((2E)-N-[(5R,6S)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.0490nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274178((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274256((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274255((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274175((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.166nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274214((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274212((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274349(CHEMBL491075 | N-[(5R,6S)-17-(Cyclopropylmethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274348((2E)-N-[(5R,6S)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.420nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274017((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.457nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274177((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.470nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274257((2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274016((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.647nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274179((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274520((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.869nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)copy SMILEScopy InChI
Affinity DataIC50: 1.12nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig ileum assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274213((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274775(CHEMBL457735 | N-hexyl-[(5R,6R)-17-(cyclopropylmet...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)copy SMILEScopy InChI
Affinity DataIC50: 2.35nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274015(CHEMBL459978 | N-[(5R,6R)-17-(Cyclopropylmethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274721((5R,6R)-17-(cyclopropylmethyl)-4,5-epoxy-6-hexylox...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274176(CHEMBL523151 | N-[(5R,6R)-17-(Cyclopropylmethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274774(CHEMBL456659 | N-[(5R,6R)-17-(Cyclopropylmethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274482((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 27.2nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50274402((2E)-N-[(5R,6R)-4,5-Epoxy-3,14-dihydroxy-17-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries, Inc.

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RVDPubMed
TargetBile salt export pump(Rattus norvegicus)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50375575(CHEMBL270493)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 1 uM) in canalicular membrane vesicles from SD ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5H4RPubMed
TargetBile salt export pump(Rattus norvegicus)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391001(CHEMBL2074736)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 1 uM) in canalicular membrane vesicles from SD ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5H4RPubMed
TargetBile salt export pump(Rattus norvegicus)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50375575(CHEMBL270493)copy SMILEScopy InChI
Affinity DataIC50: 6.19E+4nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 1 uM) in membrane vesicles isolated from Bsep-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5H4RPubMed
TargetBile salt export pump(Rattus norvegicus)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391001(CHEMBL2074736)copy SMILEScopy InChI
Affinity DataIC50: 6.79E+4nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 1 uM) in membrane vesicles isolated from Bsep-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5H4RPubMed