TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.100nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.200nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.300nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.300nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.300nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.400nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.400nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.5nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.5nMAssay Description:The inhibitory effect of the compounds on FGFR4 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.5nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.600nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMpH: 7.4Assay Description:The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.700nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 0.700nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR1 kinase activity, a biotinylated peptide (biotin-EEPLYW...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.40nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR1 kinase activity, a biotinylated peptide (biotin-EEPLYW...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.5nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.5nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.5nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
In DepthDetails
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 1.70nMAssay Description:The inhibitory effect of the compounds on FGFR4 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.
US Patent
Taiho Pharmaceutical Co., Ltd.
US Patent
Affinity DataIC50: 2nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair