Compile Data Set for Download or QSAR
Found 14 with Last Name = 'kawahara' and Initial = 'h'
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50358310(CHEMBL1922539)copy SMILEScopy InChI
Affinity DataKi:  5.24E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73QKPubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50358309(CHEMBL1922538)copy SMILEScopy InChI
Affinity DataKi:  5.38E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73QKPubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50358308(CHEMBL1922537)copy SMILEScopy InChI
Affinity DataKi:  7.89E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73QKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM20875(1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM20875(1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28N2PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50208612((-)-kurarinone | (2S)-2-(2,4-dihydroxyphenyl)-7-hy...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28N2PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50208611((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28N2PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50358310(CHEMBL1922539)copy SMILEScopy InChI
Affinity DataIC50: 8.24E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73QKPubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50358309(CHEMBL1922538)copy SMILEScopy InChI
Affinity DataIC50: 8.45E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73QKPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50208612((-)-kurarinone | (2S)-2-(2,4-dihydroxyphenyl)-7-hy...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28N2PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50358308(CHEMBL1922537)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73QKPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50312003(CHEMBL1079947 | Lorneic acid A)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human platelet PDE5 assessed as [3H]cGMP to [3H]GMP conversion pretreated 15 mins before substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NM9PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50208611((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28N2PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Nippon Suisan Kaisha, Ltd

Curated by ChEMBL
LigandPNGBDBM50312004(CHEMBL1079948 | Lorneic acid B)copy SMILEScopy InChI
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of human platelet PDE5 assessed as [3H]cGMP to [3H]GMP conversion pretreated 15 mins before substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NM9PubMed