Compile Data Set for Download or QSAR
Found 94 with Last Name = 'kawata' and Initial = 'h'
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317664(2-(trifluoromethyl)-4-(3,4,4-trimethyl-5-oxo-2-thi...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317655(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331872(5-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317656(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM35909(2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-ph...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331871(5-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317660(3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317652(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317658(2-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317657(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331870(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317654(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220941(5-(4-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331869(6-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331868(6-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331867(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331866(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331865(4-(3-Phenyl-4,4-dimethyl-5-oxo-2-thioxoimidazolidi...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317659(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220939(6-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317655(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317656(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220934(3-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220937(8-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317656(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM35909(2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-ph...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331865(4-(3-Phenyl-4,4-dimethyl-5-oxo-2-thioxoimidazolidi...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317653(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220941(5-(4-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220937(8-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317663(3-[3-(4-Cyano-2-methyl-3-trifluoromethylphenyl)-5,...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220936(5-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220934(3-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317660(3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331867(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220945(5-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220940(10-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50220945(5-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QQTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317655(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317651(4-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317652(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50331866(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S1PPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GK5PubMed
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