Compile Data Set for Download or QSAR
Found 595 with Last Name = 'khatuya' and Initial = 'h'
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116208(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50029275(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116204(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116936(1-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22564(2-arylbenzimidazole derivative, 10 | 2-{2-chloro-4...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116940(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116928(1-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50029266(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22563(2-arylbenzimidazole derivative, 9 | 2-{2-chloro-4-...)copy SMILEScopy InChI
Affinity DataKi:  9nM ΔG°:  -45.9kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116206((S)-1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethy...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116938(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116206((S)-1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethy...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50029275(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22556(2-arylbenzimidazole derivative, 2 | 2-{2-chloro-4-...)copy SMILEScopy InChI
Affinity DataKi:  22nM ΔG°:  -43.7kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116203(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116208(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22560(2-arylbenzimidazole derivative, 6 | 5-tert-butyl-2...)copy SMILEScopy InChI
Affinity DataKi:  26nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22562(2-arylbenzimidazole derivative, 8 | 5-tert-butyl-2...)copy SMILEScopy InChI
Affinity DataKi:  26nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22558(2-arylbenzimidazole derivative, 4 | 4-{2-chloro-4-...)copy SMILEScopy InChI
Affinity DataKi:  28nM ΔG°:  -43.1kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116937(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116937(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116203(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116928(1-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22555(2-arylbenzimidazole derivative, 1 | 2-{2-chloro-4-...)copy SMILEScopy InChI
Affinity DataKi:  46nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22561(2-arylbenzimidazole derivative, 7 | 5-tert-butyl-2...)copy SMILEScopy InChI
Affinity DataKi:  65nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116940(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  66nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116935(8-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  82nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116931(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)copy SMILEScopy InChI
Affinity DataKi:  86nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116205(1-(5-Bromo-thiophen-2-ylmethyl)-4-(2-methoxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  92nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116204(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  92nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22557(2-arylbenzimidazole derivative, 3 | 5-tert-butyl-2...)copy SMILEScopy InChI
Affinity DataKi:  93nM ΔG°:  -40.1kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116936(1-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  105nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22565(2-arylbenzimidazole lead compound 1 | 5-chloro-2-{...)copy SMILEScopy InChI
Affinity DataKi:  124nM ΔG°:  -39.4kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116205(1-(5-Bromo-thiophen-2-ylmethyl)-4-(2-methoxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  128nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116202(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116201(CHEMBL302495 | {5-[4-(2-Methoxy-phenyl)-piperazin-...)copy SMILEScopy InChI
Affinity DataKi:  138nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116938(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116201(CHEMBL302495 | {5-[4-(2-Methoxy-phenyl)-piperazin-...)copy SMILEScopy InChI
Affinity DataKi:  202nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22559(1-{3-[4-(5-tert-butyl-1H-1,3-benzodiazol-2-yl)-2-c...)copy SMILEScopy InChI
Affinity DataKi:  250nM ΔG°:  -37.7kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P0XB5PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116208(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  259nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116212(5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-thio...)copy SMILEScopy InChI
Affinity DataKi:  262nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116931(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)copy SMILEScopy InChI
Affinity DataKi:  285nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116939(2-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  297nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB528DPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116200(CHEMBL303485 | {5-[4-(2-Propoxy-phenyl)-piperazin-...)copy SMILEScopy InChI
Affinity DataKi:  331nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
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