Compile Data Set for Download or QSAR
Found 207 with Last Name = 'nagasawa' and Initial = 'h'
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84868(Swainsonine derivative, 3)copy SMILEScopy InChI
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84869(Swainsonine derivative, 4)copy SMILEScopy InChI
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84867(Swainsonine derivative, 2)copy SMILEScopy InChI
Affinity DataKi:  2.80nM ΔG°:  -48.8kJ/mole IC50: 30nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.6kJ/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386618(CHEMBL2048443)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04VSPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50173539(1-(4-Hydroxy-5-trityloxymethyl-tetrahydro-furan-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82BB5PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50241727((S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic ac...)copy SMILEScopy InChI
Affinity DataKi:  5.32E+4nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KKPPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50247140(CHEMBL470328 | TX-2236 | [5-(1-Oxido-1,2,4-benzotr...)copy SMILEScopy InChI
Affinity DataKi:  7.63E+4nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KKPPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50247142(CHEMBL470329 | TX-2228 | [4-(1-Oxido-1,2,4-benzotr...)copy SMILEScopy InChI
Affinity DataKi:  8.71E+4nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KKPPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50247141(CHEMBL443424 | TX-2235 | [5-(1,4-Dioxido-1,2,4-ben...)copy SMILEScopy InChI
Affinity DataKi:  1.97E+5nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KKPPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50247143(CHEMBL513210 | TX-2234 | [4-(1,4-Dioxido-1,2,4-ben...)copy SMILEScopy InChI
Affinity DataKi:  3.67E+5nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase (unknown origin) in aerobic conditionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66KKPPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101748(CHEMBL2057911 | US8530490, 8)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82BB5PubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50391352(CHEMBL2147981)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50391350(CHEMBL2147979)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395031(CHEMBL2163854)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50391347(CHEMBL2147976)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50391351(CHEMBL2147980)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101889(CHEMBL2057599 | US8530490, 159)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82BB5PubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101889(CHEMBL2057599 | US8530490, 159)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50166106(CHEMBL436283 | N-{3-[(2S,5S,8S,14R)-5-(3-Guanidino...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]SDF1 from human CXCR4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95FPPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101847(CHEMBL2147985 | US8530490, 110)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101763(CHEMBL2057909 | US8530490, 23)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82BB5PubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101763(CHEMBL2057909 | US8530490, 23)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101842(CHEMBL2147986 | US8530490, 105)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84871(Swainsonine derivative, 6)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395047(CHEMBL2163852)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50388166(CHEMBL2057910)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82BB5PubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395030(CHEMBL2163866)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101906(CHEMBL2147975 | US8530490, 178)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50391348(CHEMBL2147977)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50391341(CHEMBL2147987)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386595(CHEMBL2048477)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04VSPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395044(CHEMBL2163856)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395037(CHEMBL2163863)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395035(CHEMBL2163865)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395043(CHEMBL2163857)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395032(CHEMBL2163851)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386611(CHEMBL2048476)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04VSPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84870(Swainsonine derivative, 5)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84872(Swainsonine derivative, 7)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386614(CHEMBL2048480)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04VSPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386603(CHEMBL2046464)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04VSPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386615(CHEMBL2048481)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04VSPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386636(CHEMBL1234349)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386636(CHEMBL1234349)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101766(CHEMBL2057600 | US8530490, 26)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82BB5PubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM101766(CHEMBL2057600 | US8530490, 26)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50391349(CHEMBL2147978)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53MZWPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50386605(CHEMBL2048469)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of human dUTPase using [5-3H]dUTP as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04VSPubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50395034(CHEMBL2163867)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WJRPubMed
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