Compile Data Set for Download or QSAR
Found 298 with Last Name = 'sootome' and Initial = 'h'
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161438(US10124003, Ex. Compound 51 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161392(US10124003, Ex. Compound 5 | US10835536, Ex. Comp ...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161438(US10124003, Ex. Compound 51 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161453(US10124003, Ex. Compound 66 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161438(US10124003, Ex. Compound 51 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N26F5US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161438(US10124003, Ex. Compound 51 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27XBQUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161453(US10124003, Ex. Compound 66 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N26F5US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161453(US10124003, Ex. Compound 66 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27XBQUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161426(US10124003, Ex. Compound 39 | US10894048, Ex Comp ...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161419(US10124003, Ex. Compound 32 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155569(US10092556, Example 13 | US9012475, 13 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155568(US10092556, Example 12 | US9012475, 12 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50614182(CHEMBL5291403)copy SMILES
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155565(US10092556, Example 1 | US9012475, 1 | US9346787, ...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM472833(US10835536, Ex. Comp 39)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N26F5US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161419(US10124003, Ex. Compound 32 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N26F5US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161426(US10124003, Ex. Compound 39 | US10894048, Ex Comp ...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27XBQUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161419(US10124003, Ex. Compound 32 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27XBQUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155569(US10092556, Example 13 | US9012475, 13 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155568(US10092556, Example 12 | US9012475, 12 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155565(US10092556, Example 1 | US9012475, 1 | US9346787, ...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155569(US10092556, Example 13 | US9012475, 13 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77Z2US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155568(US10092556, Example 12 | US9012475, 12 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77Z2US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155565(US10092556, Example 1 | US9012475, 1 | US9346787, ...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77Z2US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155566(US10092556, Example 2 | US9012475, 2 | US9346787, ...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155566(US10092556, Example 2 | US9012475, 2 | US9346787, ...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77Z2US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155566(US10092556, Example 2 | US9012475, 2 | US9346787, ...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155574(US10092556, Example 24 | US9012475, 24 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155574(US10092556, Example 24 | US9012475, 24 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77Z2US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155574(US10092556, Example 24 | US9012475, 24 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161434(US10894048, Ex Comp 47 | US9108973, 47)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161392(US10124003, Ex. Compound 5 | US10835536, Ex. Comp ...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Purified recombinant human FGFR4 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161440(US10124003, Ex. Compound 53 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27XBQUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77Z2US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155567(US10092556, Example 11 | US9012475, 11 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77Z2US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM47238(US9012475, MLN8237)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.4Assay Description:The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161440(US10124003, Ex. Compound 53 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161440(US10124003, Ex. Compound 53 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N26F5US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155567(US10092556, Example 11 | US9012475, 11 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155567(US10092556, Example 11 | US9012475, 11 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155573(US10092556, Example 22 | US9012475, 22 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155575(US10092556, Example 28 | US9012475, 28 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155573(US10092556, Example 22 | US9012475, 22 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FWZUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161439(US10124003, Ex. Compound 52 | US10894048, Ex Comp ...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161449(US9108973, 62)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155573(US10092556, Example 22 | US9012475, 22 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77Z2US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM155575(US10092556, Example 28 | US9012475, 28 | US9346787...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6V8BUS Patent
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