Compile Data Set for Download or QSAR
Found 20 with Last Name = 'yokoo' and Initial = 'h'
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550011(CHEMBL4747168)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HPGDSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human HPGDS using [14C]-PGH2 as substrate preincubated for 1 min in presence of MgCl2 followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50587271(CHEMBL5075403)copy SMILES
Affinity DataIC50: 140nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157KTPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50587270(CHEMBL5076100)copy SMILES
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157KTPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157KTPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 211nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V4106TPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550010(CHEMBL4762935)copy SMILES
Affinity DataIC50: 266nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550009(CHEMBL4758395)copy SMILES
Affinity DataIC50: 300nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550010(CHEMBL4762935)copy SMILES
Affinity DataIC50: 320nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550009(CHEMBL4758395)copy SMILES
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetProgesterone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50587264(CHEMBL5077912)copy SMILES
Affinity DataEC50: >125nMAssay Description:Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7SBCPubMed
TargetProgesterone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50587263(NORGESTOMET | Norgestomet | SC-21009)copy SMILES
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7SBCPubMed
TargetProgesterone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)copy SMILEScopy InChI
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7SBCPubMedDrugBank