Compile Data Set for Download or QSAR
Found 25 with Last Name = 'simmons' and Initial = 'ha'
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 0.354nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346031(6-{4-Cyano-3-[(R)-2-hydroxy-3-(2-indan-2-yl-1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50471710(CHEMBL317748)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZGSPubMed
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM20606((5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phe...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50471711(CHEMBL98892)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZGSPubMed
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM20606((5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phe...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346032(6-[2-((R)-1-{(R)-3-[2-(3-Chloro-4-methyl-phenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50161093((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346033(6-(4-Cyano-3-{(R)-3-[2-(3-fluoro-4-methyl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50318873((1S,2S,3R,4R,5S)-6-{2-[(1R)-1-[(2R)-3-{[1-(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50246060(CHEMBL472212 | CHEMBL541649 | D3RKN_6 | N-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant PYK2More data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50065941(1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZGSPubMed
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50471707(CHEMBL98116)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZGSPubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346034(6-[2-((R)-1-{(R)-3-[2-(4-Chloro-2-fluoro-phenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346035(6-{3,4-Difluoro-5-[(R)-2-hydroxy-3-(2-indan-2-yl-1...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50471709(CHEMBL421389)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZGSPubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346036(CHEMBL1198855 | Ronacaleret)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetEstrogen receptor beta(RAT)
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50471708(CHEMBL100303)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZGSPubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346037(6-(4-Fluoro-3-{(R)-3-[2-(3-fluoro-4-methyl-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346036(CHEMBL1198855 | Ronacaleret)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Negative allosteric modulator activity at rat calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346038(6-(4-Cyano-3-{(R)-3-[1,1-dimethyl-2-(1-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346039(6-{3-[(R)-2-Hydroxy-3-(2-indan-2-yl-1,1-dimethyl-e...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346040(6-(3-{(R)-3-[2-(3-Fluoro-4-methyl-phenyl)-1,1-dime...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346041(6-(2-{(R)-1-[(R)-2-Hydroxy-3-(2-indan-2-yl-1,1-dim...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed