Compile Data Set for Download or QSAR
Found 36 with Last Name = 'osborne' and Initial = 'he'
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063687(CHEMBL3397339)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063689(CHEMBL3397337)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063755(CHEMBL3397341)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063688(CHEMBL3397338)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063686(CHEMBL3397340)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM19968((2R,6S,7R)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)copy SMILEScopy InChI
Affinity DataKi:  0.190nM ΔG°:  -54.9kJ/mole EC50:  0.660nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063690(CHEMBL3397336)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063754(CHEMBL3397342)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063689(CHEMBL3397337)copy SMILEScopy InChI
Affinity DataKi:  0.350nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063687(CHEMBL3397339)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063691(CHEMBL3397335)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063755(CHEMBL3397341)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataKi:  0.540nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063751(CHEMBL3397344)copy SMILEScopy InChI
Affinity DataKi:  0.640nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063693(CHEMBL3397333)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063750(CHEMBL3397345)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063692(CHEMBL3397334)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063690(CHEMBL3397336)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM19969((2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)copy SMILEScopy InChI
Affinity DataKi:  1.54nM ΔG°:  -49.8kJ/mole EC50:  3.61nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014SVPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063688(CHEMBL3397338)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM19968((2R,6S,7R)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)copy SMILEScopy InChI
Affinity DataKi:  2.68nM ΔG°:  -48.4kJ/mole EC50:  19.4nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063686(CHEMBL3397340)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063695(CHEMBL3397346)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063691(CHEMBL3397335)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063694(CHEMBL3397347)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063754(CHEMBL3397342)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063693(CHEMBL3397333)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM19969((2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)copy SMILEScopy InChI
Affinity DataKi:  14.5nM ΔG°:  -44.3kJ/mole EC50:  32.5nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N014SVPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063692(CHEMBL3397334)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063751(CHEMBL3397344)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063750(CHEMBL3397345)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063695(CHEMBL3397346)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063694(CHEMBL3397347)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataEC50:  406nMAssay Description:Agonist activity at TRbeta (unknown origin) expressed in human HuH7 cells after 24 hrs by Gal4 CTF cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataEC50:  2.47E+3nMAssay Description:Agonist activity at TRalpha (unknown origin) expressed in human HuH7 cells after 24 hrs by Gal4 CTF cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed