Compile Data Set for Download or QSAR
Found 16 with Last Name = 'ashour' and Initial = 'hf'
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50551188(CHEMBL4778826)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of EGFR in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50551188(CHEMBL4778826)copy SMILES
Affinity DataIC50: 47nMAssay Description:Inhibition of HDAC8 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetTranscription factor p65(Homo sapiens (Human))TBA
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of NFkappaB p65 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of HDAC8 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of VEGFR2 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
TargetTranscription factor p65(Homo sapiens (Human))TBA
LigandPNGBDBM50551188(CHEMBL4778826)copy SMILES
Affinity DataIC50: 134nMAssay Description:Inhibition of NFkappaB p65 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50551188(CHEMBL4778826)copy SMILES
Affinity DataIC50: 388nMAssay Description:Inhibition of VEGFR2 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of HDAC1 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of HDAC2 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of HDAC3 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50551188(CHEMBL4778826)copy SMILES
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of HDAC1 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50551188(CHEMBL4778826)copy SMILES
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HDAC2 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50551188(CHEMBL4778826)copy SMILES
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC3 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of HDAC6 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50551188(CHEMBL4778826)copy SMILES
Affinity DataIC50: 9.99E+5nMAssay Description:Inhibition of HDAC6 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M69BVPubMed