Compile Data Set for Download or QSAR
Found 37 with Last Name = 'chan' and Initial = 'hk'
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6745(1,7-Annulated indolocarbazole deriv. 13Ab | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6756(1,7-Annulated indolocarbazole deriv. 16-b | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6747(1,7-Annulated indolocarbazole deriv. 13Bc | 7-brom...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6749(1,7-Annulated indolocarbazole deriv. 13Be | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6742(1,7-Annulated indolocarbazole deriv. 13Aa | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 18nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6746(1,7-Annulated indolocarbazole deriv. 13Bb | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6748(1,7-Annulated indolocarbazole deriv. 13Bd | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 23nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6744(1,7-Annulated indolocarbazole deriv. 13Ca | 23-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6755(1,7-Annulated indolocarbazole deriv. 16-a | 24-(ch...)copy SMILEScopy InChI
Affinity DataIC50: 64nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6743(1,7-Annulated indolocarbazole deriv. 13Ba | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 71nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6752(1,7-Annulated indolocarbazole deriv. 13Bf | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 72nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6745(1,7-Annulated indolocarbazole deriv. 13Ab | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 79nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6754(1,7-Annulated indolocarbazole deriv. 13Bg | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 84nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6750(1,7-Annulated indolocarbazole deriv. 13Da | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 126nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6746(1,7-Annulated indolocarbazole deriv. 13Bb | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 141nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6751(1,7-Annulated indolocarbazole deriv. 13Af | 26-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 175nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6753(1,7-Annulated indolocarbazole deriv. 13Cf | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 210nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6743(1,7-Annulated indolocarbazole deriv. 13Ba | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 217nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6742(1,7-Annulated indolocarbazole deriv. 13Aa | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 219nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6749(1,7-Annulated indolocarbazole deriv. 13Be | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 284nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6756(1,7-Annulated indolocarbazole deriv. 16-b | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 383nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6754(1,7-Annulated indolocarbazole deriv. 13Bg | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 650nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6758(1,4-dimethyl 2-[({7-fluoro-13,15-dioxo-1,4,14-tria...)copy SMILEScopy InChI
Affinity DataIC50: 671nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6742(1,7-Annulated indolocarbazole deriv. 13Aa | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 858nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6757(1,7-Annulated indolocarbazole deriv. 16-c | 24-[(d...)copy SMILEScopy InChI
Affinity DataIC50: 898nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6752(1,7-Annulated indolocarbazole deriv. 13Bf | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6751(1,7-Annulated indolocarbazole deriv. 13Af | 26-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6752(1,7-Annulated indolocarbazole deriv. 13Bf | 25-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6747(1,7-Annulated indolocarbazole deriv. 13Bc | 7-brom...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Lilly Research Laboratories

LigandPNGBDBM6759((2S)-1-({7-fluoro-13,15-dioxo-1,4,14-triazaheptacy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6748(1,7-Annulated indolocarbazole deriv. 13Bd | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6747(1,7-Annulated indolocarbazole deriv. 13Bc | 7-brom...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6746(1,7-Annulated indolocarbazole deriv. 13Bb | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6745(1,7-Annulated indolocarbazole deriv. 13Ab | 7-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6744(1,7-Annulated indolocarbazole deriv. 13Ca | 23-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6743(1,7-Annulated indolocarbazole deriv. 13Ba | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Lilly Research Laboratories

LigandPNGBDBM6749(1,7-Annulated indolocarbazole deriv. 13Be | 24-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP. 33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W3HPubMed