Compile Data Set for Download or QSAR
Found 1862 with Last Name = 'chan' and Initial = 'hm'
LigandPNGBDBM451038(8-(4-((dimethylamino)methyl)phenyl)-N-(2-fluoro- |...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM451065(US10676479, Example 95 | ethyl 5-(((5-fluoro-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM451070(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)- |...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM451062(US10676479, Example 92 | ethyl 5-(((5-fluoro-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM291686(8-(1,3-Dimethyl-1H-pyrazol-5-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291686(8-(1,3-Dimethyl-1H-pyrazol-5-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291695(3-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291695(3-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291815((5-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291815((5-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291908(8-(6-((dimethylamino)methyl)-2-methylpyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291925(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
LigandPNGBDBM291908(8-(6-((dimethylamino)methyl)-2-methylpyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291925(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291909(8-(6-ethyl-4-methylpyridin-3-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMpH: 8.0Assay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291909(8-(6-ethyl-4-methylpyridin-3-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291824(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291824(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291824(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291824(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 8.0Assay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291814((5-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291909(8-(6-ethyl-4-methylpyridin-3-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMpH: 8.0Assay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291909(8-(6-ethyl-4-methylpyridin-3-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291814((5-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291823(8-(4-chloro-6-methoxypyridin-3-yl)-N-((5-fluoro-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291823(8-(4-chloro-6-methoxypyridin-3-yl)-N-((5-fluoro-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMpH: 8.0Assay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291853(8-(2-(difluoromethyl)pyridin-3-yl)-N-((5-fluoro-2,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291918(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM451065(US10676479, Example 95 | ethyl 5-(((5-fluoro-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM291918(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
LigandPNGBDBM450978(1-Chloro-8-(2,4-dimethylpyrimidin-5-yl)-N-((5-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM291853(8-(2-(difluoromethyl)pyridin-3-yl)-N-((5-fluoro-2,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
LigandPNGBDBM291689(N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291689(N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM451074(8-(2,4-dimethylpyrimidin-5-yl)-1-(ethylsulfonyl)- ...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM291882(8-(6-(difluoromethoxy)-4-methylpyridin-3-yl)-N-((5...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 8.0Assay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
LigandPNGBDBM291909(8-(6-ethyl-4-methylpyridin-3-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291909(8-(6-ethyl-4-methylpyridin-3-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291882(8-(6-(difluoromethoxy)-4-methylpyridin-3-yl)-N-((5...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM451053(8-(2-(3,5-dimethylpiperazin-1-yl)-4- | US10676479,...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM450981(8-(2-(Difluoromethyl)pyridin-3-yl)-N-((5-fluoro-2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM291873(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMpH: 8.0Assay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291873(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM291879(8-(2,5-dimethylpyridin-4-yl)-N-((5-fluoro-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 8.0Assay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291880(8-(1,3-dimethyl-1H-pyrazol-4-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291830(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291879(8-(2,5-dimethylpyridin-4-yl)-N-((5-fluoro-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
LigandPNGBDBM451072(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)- |...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM451054(5-(((5-fluoro-2,3-dihydrobenzofuran-4- | US1067647...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM291880(8-(1,3-dimethyl-1H-pyrazol-4-yl)-N-((5-fluoro-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Cell lysates were transferred to the wells of a 384-well plate and the final volume was adjusted to 50 μL per well with PBS. The plate was seale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MD7US Patent
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