Compile Data Set for Download or QSAR
Found 26 with Last Name = 'cox' and Initial = 'hm'
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataKi:  0.0631nMAssay Description:Effect on pancreatic polypeptide-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Effect on neuropeptide Y-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Effect on peptide YY-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell mem...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563421(CHEMBL4745232)copy SMILES
Affinity DataIC50: 2.51E+3nMAssay Description:Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VGBPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563421(CHEMBL4745232)copy SMILES
Affinity DataIC50: 2.70E+3nMAssay Description:Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VGBPubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))TBA
LigandPNGBDBM50563421(CHEMBL4745232)copy SMILES
Affinity DataIC50: 3.80E+3nMAssay Description:Allosteric antagonist activity at NPY5R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport by electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VGBPubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))TBA
LigandPNGBDBM50563421(CHEMBL4745232)copy SMILES
Affinity DataIC50: 3.80E+3nMAssay Description:Allosteric antagonist activity at NPY5R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport by electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VGBPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563420(CHEMBL4780125)copy SMILES
Affinity DataIC50: 3.98E+3nMAssay Description:Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VGBPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50563420(CHEMBL4780125)copy SMILES
Affinity DataIC50: 4.00E+3nMAssay Description:Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VGBPubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  0.0631nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY2 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  3.20nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY5 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  0.400nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  845nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of peptide YY-induced ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  0.501nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  398nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of neuropeptide Y-indu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  5.01E+3nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  0.0398nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY1 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  5.10E+3nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  794nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of peptide YY-induced ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of pancreatic polypept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  0.398nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  0.0398nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  443nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of neuropeptide Y-indu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  4.5nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of pancreatic polypept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  0.0300nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)copy SMILEScopy InChI
Affinity DataEC50:  0.5nMAssay Description:Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B915RPubMed