Compile Data Set for Download or QSAR
Found 158 with Last Name = 'chang' and Initial = 'hw'
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50006811(2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329397(CHEMBL1269648 | N-(4-Ethylphenyl)-5-methylbenzo[d]...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N256MPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145514((E)-1-Furan-2-yl-3-pyridin-2-yl-propenone | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women's University

Curated by ChEMBL
LigandPNGBDBM50128343(CHEMBL3629176)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N256MPubMed
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women's University

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N256MPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329394(5-Chloro-N-(4-ethylphenyl)benzo[d]oxazol-2-amine |...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329392(CHEMBL1269619 | N-(4-Ethylphenyl)benzo[d]oxazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women's University

Curated by ChEMBL
LigandPNGBDBM50128342(CHEMBL3629175)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+3nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N256MPubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibitory activity against murine prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50128342(CHEMBL3629175)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N256MPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145514((E)-1-Furan-2-yl-3-pyridin-2-yl-propenone | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50254381(2-(4-methoxyphenyl)-6-(4-oxo-2-phenyl-4H-chromen-7...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3153PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50254327(2-(2,4-dimethoxyphenyl)-6-(4-oxo-2-phenyl-4H-chrom...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3153PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329404(CHEMBL1269727 | N-(3-Bromophenyl)-5-methoxybenzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329402(CHEMBL1269907 | N-(4-Isopropylphenyl)-5-methoxyben...)copy SMILEScopy InChI
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329403(5-Methoxy-N-(4-(methylthio)phenyl)benzo[d]oxazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183248(2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72VZPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145509((E)-1,3-Di-thiophen-2-yl-propenone | CHEMBL88104)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183250(2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z72VZPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50128343(CHEMBL3629176)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N256MPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329393(5-Chloro-N-phenylbenzo[d]oxazol-2-amine | CHEMBL12...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329396(5-Methyl-N-phenylbenzo[d]oxazol-2-amine | CHEMBL12...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145509((E)-1,3-Di-thiophen-2-yl-propenone | CHEMBL88104)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N256MPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145507((E)-1-Pyridin-2-yl-3-thiophen-3-yl-propenone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 5.22E+3nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329398(CHEMBL1269649 | N-(2-Ethylphenyl)-5-methylbenzo[d]...)copy SMILEScopy InChI
Affinity DataIC50: 5.66E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145518((E)-3-Thiophen-3-yl-1-thiophen-2-yl-propenone | CH...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183248(2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1D5GPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145515((E)-3-(3-Methyl-thiophen-2-yl)-1-pyridin-2-yl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 6.51E+3nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329400(CHEMBL1269704 | N-(3-Methoxyphenyl)-5-methylbenzo[...)copy SMILEScopy InChI
Affinity DataIC50: 6.83E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329399(6-Methyl-N-(4-(methylthio)phenyl)benzo[d]oxazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145516((E)-3-Furan-2-yl-1-pyridin-2-yl-propenone | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 7.44E+3nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145506((E)-1-(5-Chloro-thiophen-2-yl)-3-furan-2-yl-propen...)copy SMILEScopy InChI
Affinity DataIC50: 7.52E+3nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145507((E)-1-Pyridin-2-yl-3-thiophen-3-yl-propenone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50329401(5-Methoxy-N-phenylbenzo[d]oxazol-2-amine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 7.88E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145504((E)-3-Furan-3-yl-1-pyridin-3-yl-propenone | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 7.92E+3nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50047342((E)-3-Phenyl-1-pyridin-2-yl-propenone | 3-Phenyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183244(3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 8.42E+3nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1D5GPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM49481(1,3-benzoxazol-2-yl(phenyl)amine | CHEMBL1269508 |...)copy SMILEScopy InChI
Affinity DataIC50: 8.91E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79BMCPubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145509((E)-1,3-Di-thiophen-2-yl-propenone | CHEMBL88104)copy SMILEScopy InChI
Affinity DataIC50: 9.01E+3nMAssay Description:Inhibitory activity against murine prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145505((E)-1-Pyridin-2-yl-3-thiophen-2-yl-propenone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 9.01E+3nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145511((E)-1-Phenyl-3-(thiophen-2-yl)prop-2-en-1-one | (E...)copy SMILEScopy InChI
Affinity DataIC50: 9.02E+3nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145511((E)-1-Phenyl-3-(thiophen-2-yl)prop-2-en-1-one | (E...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50254380(6,7'-oxybis(2-(2,4-dihydroxyphenyl)-4H-chromen-4-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3153PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145510((E)-1-Pyridin-3-yl-3-thiophen-3-yl-propenone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against lipoxygenase-2 in micceMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50145505((E)-1-Pyridin-2-yl-3-thiophen-2-yl-propenone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7005PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254380(6,7'-oxybis(2-(2,4-dihydroxyphenyl)-4H-chromen-4-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3153PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50253965(2-(4-hydroxyphenyl)-7-(2-(2-hydroxyphenyl)-4-oxo-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3153PubMed
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