Compile Data Set for Download or QSAR
Found 369 with Last Name = 'antes' and Initial = 'i'
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8891(3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...)copy SMILEScopy InChI
Affinity DataKi:  1.30nM IC50: 2nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8890(3-(5-Methoxy-1H-inden-2-yl)pyridine | indene 3)copy SMILEScopy InChI
Affinity DataKi:  2.60nM IC50: 4nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8889(3-(3,4-Dihydronaphthalen-2-yl)pyridine | Dihydrona...)copy SMILEScopy InChI
Affinity DataKi:  4.60nM IC50: 7nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8888(3-(1H-Inden-2-yl)pyridine | US9271963, 32 | indene...)copy SMILEScopy InChI
Affinity DataKi:  8.40nM IC50: 13nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50253499(4-(3-Pyridin-3-yl-naphthalen-2-ylmethyl)benzonitri...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50253574(4-[3-(4-Methoxybenzyl)naphthalen-2-yl]isoquinoline...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8909(6-(pyridin-3-yl)naphthalene-2-carbonitrile | 6-Pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8881(5-[(E)-(5-Chloro-2,3-dihydro-1H-inden-1-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50253545(3-[3-(4-Trifluoromethoxybenzyl)naphthalen-2-yl]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8894(3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50253575(4-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]is...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8905(3-(6-Methoxy-2-naphthyl)pyridine | 3-(6-methoxynap...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8873(5-[(1E)-2,3-dihydro-1H-inden-1-ylidenemethyl]-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8905(3-(6-Methoxy-2-naphthyl)pyridine | 3-(6-methoxynap...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8875((5Z)-5-(1H-Imidazol-5-ylmethylene)-5,6,7,8-tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50191600(3-((1H-imidazol-1-yl)methyl)-2-(4-methoxyphenyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8586((3-Pyridylmethylene)indane 5a | 3-{[(1E)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8892(3-(1-Methyl-3,4-dihydronaphthalen-2-yl)-pyridine |...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50253548(3-Methoxy-5-[6-methoxy-3-(4-methoxybenzyl)naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50253547(3-Methoxy-5-[3-(4-methoxybenzyl)naphthalen-2-yl]py...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50253498(3-[3-(4-Methoxybenzyl)naphthalen-2-yl]pyridine | C...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8608((3-Pyridylmethylene)indane 25a | 3-{[(1E)-4-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8873(5-[(1E)-2,3-dihydro-1H-inden-1-ylidenemethyl]-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50253546(3-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]py...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50191600(3-((1H-imidazol-1-yl)methyl)-2-(4-methoxyphenyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8587((3-Pyridylmethylene)indane 5b | 3-{[(1Z)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8581((3-Pyridylmethylene)indane 1a | 3-[(1E)-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8879(5-[(E)-(5-Fluoro-2,3-dihydro-1H-inden-1-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 11.2nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8908(3-(6-Ethoxy-2-naphthyl)pyridine | 3-(6-ethoxynapht...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM50191599(3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BP4PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8932(1-Methyl-5-(2-naphthyl)-1H-imidazole | 1-methyl-5-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8876((1E)-1-(1H-Imidazol-5-ylmethylene)indane-5-carboni...)copy SMILEScopy InChI
Affinity DataIC50: 12.3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8910(3-(5-Chloro-6-methoxy-2-naphthyl)pyridine | 3-(5-c...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8895(3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8879(5-[(E)-(5-Fluoro-2,3-dihydro-1H-inden-1-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 13.9nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8876((1E)-1-(1H-Imidazol-5-ylmethylene)indane-5-carboni...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8907(3-(6-Bromo-2-naphthyl)pyridine | 3-(6-bromonaphtha...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8876((1E)-1-(1H-Imidazol-5-ylmethylene)indane-5-carboni...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
Displayed 1 to 50 (of 369 total ) | Next | Last >>
Jump to: