Compile Data Set for Download or QSAR
Found 211 with Last Name = 'bennacef' and Initial = 'i'
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281656(US10022461, Compound 126)copy SMILEScopy InChI
Affinity DataKi:  0.180nM ΔG°:  -55.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Agonistic activity at DRD3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7X7CPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281558(US10022461, Compound 9)copy SMILEScopy InChI
Affinity DataKi:  0.220nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281645(US10022461, Compound 115)copy SMILEScopy InChI
Affinity DataKi:  0.224nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281561(US10022461, Compound 13)copy SMILEScopy InChI
Affinity DataKi:  0.290nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281560(US10022461, Compound 12)copy SMILEScopy InChI
Affinity DataKi:  0.290nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281633(US10022461, Compound 103)copy SMILEScopy InChI
Affinity DataKi:  0.320nM ΔG°:  -54.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281609(US10022461, Compound 59)copy SMILEScopy InChI
Affinity DataKi:  0.330nM ΔG°:  -54.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281563(US10022461, Compound 14-1)copy SMILEScopy InChI
Affinity DataKi:  0.330nM ΔG°:  -54.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281635(US10022461, Compound 105)copy SMILEScopy InChI
Affinity DataKi:  0.383nM ΔG°:  -53.7kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281559(US10022461, Compound 11-5)copy SMILEScopy InChI
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281565(US10022461, Compound 16)copy SMILEScopy InChI
Affinity DataKi:  0.410nM ΔG°:  -53.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281639(US10022461, Compound 109)copy SMILEScopy InChI
Affinity DataKi:  0.423nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281567(US10022461, Compound 18)copy SMILEScopy InChI
Affinity DataKi:  0.430nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281566(US10022461, Compound 17)copy SMILEScopy InChI
Affinity DataKi:  0.430nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281649(US10022461, Compound 119)copy SMILEScopy InChI
Affinity DataKi:  0.438nM ΔG°:  -53.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281557(US10022461, Compound 8)copy SMILEScopy InChI
Affinity DataKi:  0.480nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281623(US10022461, Compound 75)copy SMILEScopy InChI
Affinity DataKi:  0.480nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281644(US10022461, Compound 114)copy SMILEScopy InChI
Affinity DataKi:  0.494nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281651(US10022461, Compound 121)copy SMILEScopy InChI
Affinity DataKi:  0.512nM ΔG°:  -53.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281564(US10022461, Compound 15)copy SMILEScopy InChI
Affinity DataKi:  0.530nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281626(US10022461, Compound 93)copy SMILEScopy InChI
Affinity DataKi:  0.530nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281555(US10022461, Compound 6)copy SMILEScopy InChI
Affinity DataKi:  0.540nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281630(US10022461, Compound 99)copy SMILEScopy InChI
Affinity DataKi:  0.550nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281568(US10022461, Compound 19)copy SMILEScopy InChI
Affinity DataKi:  0.620nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50414563(CHEMBL559873)copy SMILEScopy InChI
Affinity DataKi:  0.631nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7X7CPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281599(US10022461, Compound 49)copy SMILEScopy InChI
Affinity DataKi:  0.670nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281642(US10022461, Compound 112)copy SMILEScopy InChI
Affinity DataKi:  0.672nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281638(US10022461, Compound 108)copy SMILEScopy InChI
Affinity DataKi:  0.677nM ΔG°:  -52.3kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281624(US10022461, Compound 88)copy SMILEScopy InChI
Affinity DataKi:  0.690nM ΔG°:  -52.3kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281569(US10022461, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  0.75nM ΔG°:  -52.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281600(US10022461, Compound 50)copy SMILEScopy InChI
Affinity DataKi:  0.75nM ΔG°:  -52.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281622(US10022461, Compound 72)copy SMILEScopy InChI
Affinity DataKi:  0.760nM ΔG°:  -52.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281643(US10022461, Compound 113)copy SMILEScopy InChI
Affinity DataKi:  0.784nM ΔG°:  -52.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50331549(CHEMBL567286 | [11C]-3-(2-oxo-3-(2-(4-(trifluorome...)copy SMILEScopy InChI
Affinity DataKi:  0.794nMAssay Description:Antagonistic activity at rat DRD3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7X7CPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50331549(CHEMBL567286 | [11C]-3-(2-oxo-3-(2-(4-(trifluorome...)copy SMILEScopy InChI
Affinity DataKi:  0.794nMAssay Description:Antagonistic activity at human DRD3 receptor by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7X7CPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281601(US10022461, Compound 51)copy SMILEScopy InChI
Affinity DataKi:  0.870nM ΔG°:  -51.7kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281628(US10022461, Compound 95)copy SMILEScopy InChI
Affinity DataKi:  0.960nM ΔG°:  -51.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281602(US10022461, Compound 52)copy SMILEScopy InChI
Affinity DataKi:  0.980nM ΔG°:  -51.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281603(US10022461, Compound 53)copy SMILEScopy InChI
Affinity DataKi:  1.02nM ΔG°:  -51.3kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281604(US10022461, Compound 54)copy SMILEScopy InChI
Affinity DataKi:  1.05nM ΔG°:  -51.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281631(US10022461, Compound 100)copy SMILEScopy InChI
Affinity DataKi:  1.06nM ΔG°:  -51.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281654(US10022461, Compound 124)copy SMILEScopy InChI
Affinity DataKi:  1.07nM ΔG°:  -51.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281641(US10022461, Compound 111)copy SMILEScopy InChI
Affinity DataKi:  1.09nM ΔG°:  -51.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281597(US10022461, Compound 44)copy SMILEScopy InChI
Affinity DataKi:  1.13nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281629(US10022461, Compound 98)copy SMILEScopy InChI
Affinity DataKi:  1.13nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281605(US10022461, Compound 55)copy SMILEScopy InChI
Affinity DataKi:  1.14nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281632(US10022461, Compound 101)copy SMILEScopy InChI
Affinity DataKi:  1.14nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281606(US10022461, Compound 56)copy SMILEScopy InChI
Affinity DataKi:  1.16nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM281657(US10022461, Compound 127)copy SMILEScopy InChI
Affinity DataKi:  1.17nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959KK6US Patent
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