Compile Data Set for Download or QSAR
Found 148 with Last Name = 'mcalexander' and Initial = 'i'
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139601(1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(met...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190017((4R,5R)-4-(2-fluorophenyl)-5-((S)-hydroxy(5-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMedDrugBank
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139614(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139618(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190020(4-(5-((S)-hydroxy((2R,3R)-1-methyl-5-oxo-3-phenylp...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190010((4R,5R)-4-(2-fluorophenyl)-5-((S)-hydroxy(5-(pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190010((4R,5R)-4-(2-fluorophenyl)-5-((S)-hydroxy(5-(pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139621(4-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190030((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139626(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139620(5-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139597(4-(4-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139623(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190015((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190004((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139627(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(4-(5-(m...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139602(5-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139598(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139635(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190031((4R,5R)-5-((S)-hydroxy(5-(morpholinosulfonyl)thiop...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139596(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139628(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190011((4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190006((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190009((4R,5R)-5-((S)-hydroxy(5-phenylthiophen-2-yl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139606(CHEMBL168049 | N-(2-Dimethylamino-ethyl)-5-{4-[3-(...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139611(3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50167133((4R,5R)-5-[(R)-Hydroxy-(5-phenyl-thiophen-2-yl)-me...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against 17 beta hydroxysteroid dehydrogenase type 2 (type II 17-beta-HSD II)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6HW8PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139629(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139609(3-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190035((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190028((4R,5R)-5-((S)-(5-(2-fluorophenyl)thiophen-2-yl)(h...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139605(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139636(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139617(3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139612(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139613(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190006((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190006((4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(h...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139599(5-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190036((4R,5R)-5-((S)-hydroxy(5-(pyridin-2-yl)thiophen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139608(CHEMBL164827 | N-(6-Methoxy-pyridin-3-yl)-3-{4-[3-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190014((4R,5R)-5-((S)-(5-(3-(dimethylamino)phenyl)thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139630(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190008((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190008((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24V1PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139622(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
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