Compile Data Set for Download or QSAR
Found 109 with Last Name = 'mcfadyen' and Initial = 'i'
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000655((4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)copy SMILEScopy InChI
Affinity DataKi:  0.740nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071865((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Binding affinity against mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071865((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...)copy SMILEScopy InChI
Affinity DataKi:  2.62nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:Binding affinity against mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071864(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Binding affinity against mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)copy SMILEScopy InChI
Affinity DataKi:  8.5nMAssay Description:Binding affinity against mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000655((4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)copy SMILEScopy InChI
Affinity DataKi:  52nMAssay Description:Binding affinity against mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071865((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071865((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071864(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)copy SMILEScopy InChI
Affinity DataKi:  58nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071865((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Binding affinity against mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071865((S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinoli...)copy SMILEScopy InChI
Affinity DataKi:  222nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)copy SMILEScopy InChI
Affinity DataKi:  679nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMedDrugBank
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataKi:  710nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMedDrugBank
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000655((4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071864(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154HJJPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28480((2S)-3-methyl-2-({12-[(thiophen-3-ylcarbamoyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28481((2S)-3-methyl-2-{[12-({[2-(thiophen-2-yl)ethyl]car...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28481((2S)-3-methyl-2-{[12-({[2-(thiophen-2-yl)ethyl]car...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28485((2S)-2-({4-[4-(1-benzofuran-2-amido)phenyl]benzene...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28469((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28473((2S)-2-[(12-{[(2-fluoroethoxy)carbonyl]amino}-8-ox...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28479((2S)-2-({12-[(cyclopentylcarbamoyl)amino]-8-oxatri...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28480((2S)-3-methyl-2-({12-[(thiophen-3-ylcarbamoyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28472((2S)-3-methyl-2-[(12-{[(2-methylpropoxy)carbonyl]a...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28470((2S)-2-({12-[(ethoxycarbonyl)amino]-8-oxatricyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28479((2S)-2-({12-[(cyclopentylcarbamoyl)amino]-8-oxatri...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28471((2S)-3-methyl-2-({12-[(propoxycarbonyl)amino]-8-ox...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28475((2S)-2-({12-[(2-chlorophenoxycarbonyl)amino]-8-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28463((2R)-2-({11-[(methoxycarbonyl)amino]-8-oxatricyclo...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28478((2S)-2-{[12-(carbamoylamino)-8-oxatricyclo[7.4.0.0...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28476((2S)-2-({12-[(4-fluorophenoxycarbonyl)amino]-8-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28483((2S)-2-[(11-{[(2-fluoroethoxy)carbonyl]amino}-8-ox...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28473((2S)-2-[(12-{[(2-fluoroethoxy)carbonyl]amino}-8-ox...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28472((2S)-3-methyl-2-[(12-{[(2-methylpropoxy)carbonyl]a...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28471((2S)-3-methyl-2-({12-[(propoxycarbonyl)amino]-8-ox...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28474((2S)-3-methyl-2-({12-[(phenoxycarbonyl)amino]-8-ox...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28461((2S)-2-({12-methanesulfonamido-8-oxatricyclo[7.4.0...)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28456((2R)-2-({11-methanesulfonamido-8-oxatricyclo[7.4.0...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28482((2S)-2-({11-[(methoxycarbonyl)amino]-8-oxatricyclo...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28477((2S)-3-methyl-2-({12-[(4-methylphenoxycarbonyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28464((2R)-3-methyl-2-({11-[(propoxycarbonyl)amino]-8-ox...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28485((2S)-2-({4-[4-(1-benzofuran-2-amido)phenyl]benzene...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28484((2S)-2-({11-[(4-fluorophenoxycarbonyl)amino]-8-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28486((2R)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28465((2R)-3-methyl-2-[(11-{[(propan-2-yloxy)carbonyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 39nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28466((2R)-3-methyl-2-({11-[(phenoxycarbonyl)amino]-8-ox...)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28458((2R)-3-methyl-2-{[11-(propane-2-sulfonamido)-8-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928NPPubMed
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