Compile Data Set for Download or QSAR
Found 163 with Last Name = 'posner' and Initial = 'i'
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036694((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-phenylsulfany...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036687((E)-3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036698((E)-3-[3-(2-Chloro-benzylsulfanylmethyl)-4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036691((E)-3-[3-(Benzothiazol-2-ylsulfanylmethyl)-4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4293((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036694((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-phenylsulfany...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4302((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036688(2-[5-((E)-2-Carbamoyl-2-cyano-vinyl)-2-hydroxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4284((5,6-Dihydroxyindanylidene)malononitrile | 2-(5,6-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4294((2E)-3-(3,4-dihydroxyphenyl)-2-[(4-fluorophenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036686((E)-3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibitiory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036679((E)-2-Cyano-3-[4-hydroxy-3-methoxy-5-(pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4304((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4303((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpr...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036688(2-[5-((E)-2-Carbamoyl-2-cyano-vinyl)-2-hydroxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036678(3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-phen...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4305((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4295((2E)-3-(3,4-dihydroxyphenyl)-2-[(4-methylphenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4306((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2-phenylet...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036686((E)-3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036686((E)-3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4307((2E)-N-(2-chlorophenyl)-2-cyano-3-(3,4-dihydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4308((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbu...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4296((2E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-eneni...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036700((E)-3-[3-(Benzooxazol-2-ylsulfanylmethyl)-4-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4309(Tyrphostin deriv. 58 | ethyl 2-[(2E)-2-cyano-3-(3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4297((2E)-2-[(2-chlorophenyl)carbonyl]-3-(3,4-dihydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4310((2E)-2-cyano-N-cyclohexyl-3-(3,4-dihydroxyphenyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036701(2-Cyano-3-[4-hydroxy-3-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036680((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-p-tolylsulfan...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitiory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4311((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dim...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4312((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2,4-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036680((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-p-tolylsulfan...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitiory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036680((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-p-tolylsulfan...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036687((E)-3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036687((E)-3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036678(3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-phen...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036681((E)-2-Cyano-3-[3-(4,5-dihydro-thiazol-2-ylsulfanyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4313((2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036701(2-Cyano-3-[4-hydroxy-3-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4314((2E)-2-(2,3-dihydro-1H-indol-1-ylcarbonyl)-3-(3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4298((2E)-3-(3,4-dihydroxyphenyl)-2-[(4-nitrophenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036701(2-Cyano-3-[4-hydroxy-3-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4285((5,6-Dihydroxy-2-oxo-3-indolinidene)malononitrile ...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036698((E)-3-[3-(2-Chloro-benzylsulfanylmethyl)-4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036701(2-Cyano-3-[4-hydroxy-3-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitiory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036698((E)-3-[3-(2-Chloro-benzylsulfanylmethyl)-4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitiory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036689(2-(4-Hydroxy-3-methoxy-5-phenylsulfanylmethyl-benz...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036694((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-phenylsulfany...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
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