Compile Data Set for Download or QSAR
Found 29 with Last Name = 'seo' and Initial = 'i'
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253594(1-(3,4-dihydroxyphenyl)-2-[2-(4-methoxyphenyl)-2H-...)copy SMILEScopy InChI
Affinity DataKi:  2.04E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253593(2-(3,4-Dimethylphenylamino)-5-(3-furan-2-ylallylid...)copy SMILEScopy InChI
Affinity DataKi:  2.14E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)copy SMILEScopy InChI
Affinity DataKi:  2.92E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)copy SMILEScopy InChI
Affinity DataKi:  3.75E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237953(2-(4-allyl-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253594(1-(3,4-dihydroxyphenyl)-2-[2-(4-methoxyphenyl)-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253593(2-(3,4-Dimethylphenylamino)-5-(3-furan-2-ylallylid...)copy SMILEScopy InChI
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50118676(2-(2-Hydroxy-ethylsulfanyl)-3-methyl-[1,4]naphthoq...)copy SMILEScopy InChI
Affinity DataIC50: 4.56E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237953(2-(4-allyl-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 4.67E+3nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253593(2-(3,4-Dimethylphenylamino)-5-(3-furan-2-ylallylid...)copy SMILEScopy InChI
Affinity DataIC50: 5.44E+3nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)copy SMILEScopy InChI
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253594(1-(3,4-dihydroxyphenyl)-2-[2-(4-methoxyphenyl)-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50118676(2-(2-Hydroxy-ethylsulfanyl)-3-methyl-[1,4]naphthoq...)copy SMILEScopy InChI
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CMWPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in pooled mixed-gender human liver microsomes using testosterone substrate in presence of NADPH pre-incubated for 3 mins by HPLC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HTQPubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50385630(CHEMBL2043144)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate incubated for 3 mins prior to NAPDH-addition measured after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0G5DPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of CYP3A4 in pooled mixed-gender human liver microsomes using triazolam substrate in presence of NADPH pre-incubated for 3 mins by HPLC-UV...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HTQPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of CYP3D6 in pooled mixed-gender human liver microsomes using dextromethorphan substrate in presence of NADPH pre-incubated for 3 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HTQPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50385630(CHEMBL2043144)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate incubated for 3 mins prior to NAPDH-addition measured after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0G5DPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50385630(CHEMBL2043144)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using triazolam as substrate incubated for 3 mins prior to NAPDH-addition measured after 30 mins by RP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0G5DPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50385630(CHEMBL2043144)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 3 mins prior to NAPDH-addition measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0G5DPubMed
TargetUDP-glucuronosyltransferase 1-6(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of of UGT1A6 in pooled mixed-gender human liver microsomes using 4-methylumbelliferone substrate by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HTQPubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of of UGT1A9 in pooled mixed-gender human liver microsomes using 4-methylumbelliferone substrate by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HTQPubMed
TargetUDP-glucuronosyltransferase 2B7(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of of UGT3B7 in pooled mixed-gender human liver microsomes using 4-methylumbelliferone substrate by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HTQPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of of UGT1A1 in pooled mixed-gender human liver microsomes using 4-methylumbelliferone substrate by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5HTQPubMed