Compile Data Set for Download or QSAR
Found 40 with Last Name = 'theret' and Initial = 'i'
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145864(CHEMBL3763283)copy SMILEScopy InChI
Affinity DataEC50:  2.93E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50533464(CHEMBL4457828)copy SMILEScopy InChI
Affinity DataKd:  4.40E+3nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SHMPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145866(CHEMBL3765780)copy SMILEScopy InChI
Affinity DataEC50:  194nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145867(CHEMBL3764630)copy SMILEScopy InChI
Affinity DataEC50:  148nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145870(CHEMBL3763700)copy SMILEScopy InChI
Affinity DataEC50:  695nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145871(CHEMBL3764668)copy SMILEScopy InChI
Affinity DataEC50:  115nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145874(CHEMBL3764079)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145875(CHEMBL3765270)copy SMILEScopy InChI
Affinity DataEC50:  263nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145876(CHEMBL3763295)copy SMILEScopy InChI
Affinity DataEC50:  535nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145877(CHEMBL3765330)copy SMILEScopy InChI
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145878(CHEMBL3765466)copy SMILEScopy InChI
Affinity DataEC50:  1.87E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145879(CHEMBL3765684)copy SMILEScopy InChI
Affinity DataEC50:  6.63E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145880(CHEMBL3765430)copy SMILEScopy InChI
Affinity DataEC50:  3.83E+4nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145881(CHEMBL3763855)copy SMILEScopy InChI
Affinity DataEC50:  3.29E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145882(CHEMBL3764856)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145883(CHEMBL3764328)copy SMILEScopy InChI
Affinity DataEC50:  638nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145885(CHEMBL3764824)copy SMILEScopy InChI
Affinity DataEC50:  173nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145886(CHEMBL3763349)copy SMILEScopy InChI
Affinity DataEC50:  608nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145887(CHEMBL3764930)copy SMILEScopy InChI
Affinity DataEC50:  342nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145888(CHEMBL3764711)copy SMILEScopy InChI
Affinity DataEC50:  688nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145889(CHEMBL3763635)copy SMILEScopy InChI
Affinity DataEC50:  1.24E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145890(CHEMBL3763775)copy SMILEScopy InChI
Affinity DataEC50:  2.05E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145892(CHEMBL3763854)copy SMILEScopy InChI
Affinity DataEC50:  810nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145894(CHEMBL3763616)copy SMILEScopy InChI
Affinity DataEC50:  1.41E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145895(CHEMBL3765308)copy SMILEScopy InChI
Affinity DataEC50:  756nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145896(CHEMBL3764342)copy SMILEScopy InChI
Affinity DataEC50:  783nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145898(CHEMBL3763162)copy SMILEScopy InChI
Affinity DataEC50:  1.15E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145898(CHEMBL3763162)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145898(CHEMBL3763162)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145899(CHEMBL3765816)copy SMILEScopy InChI
Affinity DataEC50:  1.01E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145899(CHEMBL3765816)copy SMILEScopy InChI
Affinity DataEC50:  1.01E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145899(CHEMBL3765816)copy SMILEScopy InChI
Affinity DataEC50:  255nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50346026((R)-2-(3-chloro-4-(methylsulfonyl)phenyl)-3-((R)-3...)copy SMILEScopy InChI
Affinity DataEC50:  6.32E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50346026((R)-2-(3-chloro-4-(methylsulfonyl)phenyl)-3-((R)-3...)copy SMILEScopy InChI
Affinity DataKd:  830nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50533461(CHEMBL4483049)copy SMILEScopy InChI
Affinity DataKd:  400nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SHMPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50533462(CHEMBL4534484)copy SMILEScopy InChI
Affinity DataKd:  720nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SHMPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50533463(CHEMBL4522750)copy SMILEScopy InChI
Affinity DataKd:  2.00E+3nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SHMPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM34071(benzamide derivative, 6)copy SMILEScopy InChI
Affinity DataKd:  360nMAssay Description:Binding affinity to human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluorometri...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50320996(6-(3-((S)-1-methoxypropan-2-yloxy)-5-((S)-1-phenyl...)copy SMILEScopy InChI
Affinity DataKd:  3.30E+3nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60SHMPubMed
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50145865(CHEMBL3763337)copy SMILEScopy InChI
Affinity DataEC50:  1.26E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S0FPubMed