TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 2.93E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 4.40E+3nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 194nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 148nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 695nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 115nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 263nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 535nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.87E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 6.63E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 3.83E+4nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 3.29E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 638nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 173nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 608nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 342nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 688nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.24E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 2.05E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 810nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.41E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 756nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 783nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.15E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.01E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.01E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 255nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 6.32E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 830nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 400nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 720nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 2.00E+3nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 360nMAssay Description:Binding affinity to human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluorometri...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2Z60SHMPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2Z60SHMPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 3.30E+3nMAssay Description:Displacement of TAFMT from human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluo...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataEC50: 1.26E+3nMAssay Description:Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...More data for this Ligand-Target Pair