Compile Data Set for Download or QSAR
Found 9 with Last Name = 'gonzalez valcarcel' and Initial = 'ic'
TargetInterleukin-23 receptor(Homo sapiens)
Centro de Investigaci£n Lilly S.A.

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B054GPubMed
TargetInterleukin-23 receptor(Homo sapiens)
Centro de Investigaci£n Lilly S.A.

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B054GPubMed
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50535848(CHEMBL4584997)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human SPT1 expressed in microsomes of HEK293 cells incubated for 1hr by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FR1PubMed
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50535847(CHEMBL4541898)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of human SPT1 expressed in microsomes of HEK293 cells incubated for 1hr by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FR1PubMed
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50461646(CHEBI:582124 | Myriocin)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50535848(CHEMBL4584997)copy SMILEScopy InChI
Affinity DataEC50:  977nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FR1PubMed
TargetInterleukin-23 receptor(Homo sapiens)
Centro de Investigaci£n Lilly S.A.

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)copy SMILEScopy InChI
Affinity DataKd:  1.81nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells measured over 90 secs by surface plasmon ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B054GPubMed
TargetInterleukin-23 receptor(Homo sapiens)
Centro de Investigaci£n Lilly S.A.

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)copy SMILEScopy InChI
Affinity DataKon:  0.0274M-1s-1Assay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as dissociation rate constant me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B054GPubMed
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50535847(CHEMBL4541898)copy SMILEScopy InChI
Affinity DataEC50:  4.22E+3nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FR1PubMed