Compile Data Set for Download or QSAR
Found 33 with Last Name = 'dick' and Initial = 'ie'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166790(CHEMBL364912 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel electrophysiology in inactivated state expressed in HEK293 cells using Voltage/Ion Probe Re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166787(CHEMBL195235 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel electrophysiology in inactivated state expressed in HEK293 cells using Voltage/Ion Probe Re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166785(1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-ben...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory concentration against displacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166788(1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory concentration against displacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166802(1-[3-Methoxy-2-(2-phenyl-thiazol-4-ylmethoxy)-benz...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory concentration against displacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166795(CHEMBL196036 | [2-([2,2']Bithiophenyl-5-ylmethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166801(CHEMBL196703 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166782(CHEMBL363582 | {3-Chloro-2-[2-(4-chloro-phenyl)-th...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166786(CHEMBL196392 | {2-[3-(4-Chloro-phenyl)-[1,2,4]oxad...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166787(CHEMBL195235 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vivo inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166787(CHEMBL195235 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166790(CHEMBL364912 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166793((2-{1-[2-(4-Chloro-phenyl)-thiazol-4-yl]-ethoxy}-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166785(1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-ben...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166797(CHEMBL196345 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166788(1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166791(CHEMBL197052 | [2-(Biphenyl-4-ylmethoxy)-3-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166802(1-[3-Methoxy-2-(2-phenyl-thiazol-4-ylmethoxy)-benz...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166805(Azepan-1-yl-{2-[2-(4-chloro-phenyl)-thiazol-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166803(CHEMBL371052 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166799(CHEMBL372292 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166783(CHEMBL372614 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166790(CHEMBL364912 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:In vitro inhibitory concentration against displacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166787(CHEMBL195235 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMAssay Description:In vivo inhibitory concentration against diplacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166804(Azocan-1-yl-{2-[2-(4-chloro-phenyl)-thiazol-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166792(CHEMBL193449 | [3-Methoxy-2-(3-phenyl-propoxy)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166794(CHEMBL372177 | {3-tert-Butoxy-2-[2-(4-chloro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166806(Azocan-1-yl-{2-[2-(4-chloro-phenyl)-thiazol-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166796((3-Methoxy-2-phenethyloxy-phenyl)-pyrrolidin-1-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166800(CHEMBL371314 | [3-Methoxy-2-(1-phenyl-ethoxy)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166784(CHEMBL191351 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166789(Azepan-1-yl-{2-[2-(4-chloro-phenyl)-thiazol-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166798(CHEMBL194491 | [2-(4-tert-Butyl-benzyloxy)-3-metho...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed