Found 19 with Last Name = 'aidhen' and Initial = 'is' TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Bhupat and Jyoti Mehta School of Biosciences
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in PGE2 productionMore data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Indian Institute of Technology Madras
Curated by ChEMBL
Indian Institute of Technology Madras
Curated by ChEMBL
Affinity DataEC50: 87nMAssay Description:Agonist activity at EGFP-fused TrkB receptor (unknown origin) expressed in HEK293T cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetLuciferin 4-monooxygenase(Photinus pyralis)
Indian Institute of Technology Madras
Curated by ChEMBL
Indian Institute of Technology Madras
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Activation of firefly luciferase activity expressed in HEK293T cells after 6 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Indian Institute of Technology Madras
Curated by ChEMBL
Indian Institute of Technology Madras
Curated by ChEMBL
Affinity DataEC50: 667nMAssay Description:Agonist activity at RFP-fused TrkA receptor (unknown origin) expressed in HEK293T cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
