Affinity DataIC50: 39nMAssay Description:Displacement of FITC-conjugated JQ1 from wildtype BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Displacement of FITC-conjugated JQ1 from wildtype BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Displacement of FITC-conjugated JQ1 from BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 mins by comp...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP1A2 (unknown origin) using phenacetin O-deethylation by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Displacement of FITC-conjugated JQ1 from wildtype BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 525nMAssay Description:Displacement of FITC-conjugated JQ1 from wildtype BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 min...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University of Hyderabad Campus
Curated by ChEMBL
University of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant PDE4B1 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Hyderabad Campus
Curated by ChEMBL
University of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant PDE4D2 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 863nMAssay Description:Displacement of FITC-conjugated JQ1 from BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 mins by comp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from wildtype BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 min...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University of Hyderabad Campus
Curated by ChEMBL
University of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of recombinant PDE4B1 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity to Cereblon in human Flp293T cells transfected with BRD4(BD2)-GFP fusion protein and mCherry reporter assessed as inhibition of dBET...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.99E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 mins by comp...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of NK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from wildtype BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 2.24E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 mins by comp...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Hyderabad Campus
Curated by ChEMBL
University of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of recombinant PDE4D2 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.87E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from wildtype BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 min...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Hyderabad Campus
Curated by ChEMBL
University of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of recombinant PDE4D2 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.04E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 mins by comp...More data for this Ligand-Target Pair
Affinity DataIC50: 3.13E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from wildtype BRD4 BD1 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 min...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Hyderabad Campus
Curated by ChEMBL
University of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of recombinant PDE4D2 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.51E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 mins by comp...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University of Hyderabad Campus
Curated by ChEMBL
University of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of recombinant PDE4B1 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University of Hyderabad Campus
Curated by ChEMBL
University of Hyderabad Campus
Curated by ChEMBL
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of recombinant PDE4B1 (unknown origin) expressed in Sf9 cells pre-incubated with compound for 15 mins before incubation with cAMP substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 4.65E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 mins by comp...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.97E+3nMAssay Description:Displacement of FITC-conjugated JQ1 from BRD4 BD2 (unknown origin) expressed in Escherichia coli BL21-DE3 rosetta cells incubated for 15 mins by comp...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity to Cereblon in human Flp293T cells transfected with BRD4(BD2)-GFP fusion protein and mCherry reporter assessed as inhibition of dBET...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
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