Compile Data Set for Download or QSAR
Found 345 with Last Name = 'bryans' and Initial = 'j'
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50256615((R)-3-fluoro-1-((5-fluoro-1-(1H-imidazol-2-yl)-2,3...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Binding affinity to adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24W91PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50256563((R)-2-(5-chloro-4-(methoxymethyl)-2,3-dihydro-1H-i...)copy SMILEScopy InChI
Affinity DataKi:  83nMAssay Description:Binding affinity to adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24W91PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354912(CHEMBL1837039)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354897(CHEMBL1837041)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401913(CHEMBL2207214)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401928(CHEMBL2207195)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401907(CHEMBL2207181)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401915(CHEMBL2207212)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401927(CHEMBL2207199)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401903(CHEMBL2207194)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354913(CHEMBL1837028)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354895(CHEMBL1837038)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.

US Patent
LigandPNGBDBM482266(US10918645, Example 65)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76CBUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401914(CHEMBL2207213)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401918(CHEMBL2207209)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354896(CHEMBL1837040)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401910(CHEMBL2207217)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401902(CHEMBL2207196)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.

US Patent
LigandPNGBDBM482288(8-ethyl-4-(tetrahydro-2H-pyran-4- yl)-5,11-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76CBUS Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354894(CHEMBL1837037)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401922(CHEMBL2207204)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401920(CHEMBL2207206)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401911(CHEMBL2207216)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.

US Patent
LigandPNGBDBM482268(US10918645, Example 66 | US10918645, Example 67)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76CBUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401917(CHEMBL2207210)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401906(CHEMBL2207187)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401908(CHEMBL2207180)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401901(CHEMBL2207197)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401924(CHEMBL2207202)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401912(CHEMBL2207215)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354914(CHEMBL1837017)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401909(CHEMBL2207218)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401916(CHEMBL2207211)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401905(CHEMBL2207192)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.

US Patent
LigandPNGBDBM482275(1-methyl-9-(tetrahydro-2H-pyran- 4-yl)-1,5,9,10-te...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76CBUS Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.

US Patent
LigandPNGBDBM482286(8-methyl-4-(tetrahydro-2H-pyran-4- yl)-5,11-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76CBUS Patent
TargetMAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401900(CHEMBL2207198)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MARK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401926(CHEMBL2207200)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.

US Patent
LigandPNGBDBM482290(8-isopropyl-4-(tetrahydro-2H-pyran- 4-yl)-5,11-dih...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76CBUS Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50114031((2S)-1-[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-(3,4...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401925(CHEMBL2207201)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.

US Patent
LigandPNGBDBM482277(2-ethyl-9-(tetrahydro-2H-pyran-4- yl)-2,5,9,10-tet...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76CBUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM50401921(CHEMBL2207205)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S45PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.

US Patent
LigandPNGBDBM482283(1-isopropyl-9-(tetrahydro-2H- pyran-4-yl)-1,5,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76CBUS Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354916(CHEMBL1837031)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354915(CHEMBL1837022)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50354917(CHEMBL1837027)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB179TPubMed
TargetVoltage-dependent calcium channel alpha-2 delta subunit(Sus scrofa)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50305900((+)-2-((1S,5S,6R)-6-(aminomethyl)bicyclo[3.2.0]hep...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GCQPubMed
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