Compile Data Set for Download or QSAR
Found 95 with Last Name = 'busby' and Initial = 'j'
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446517(CHEMBL3110092)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446514(CHEMBL3110076)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446515(CHEMBL3110075)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446516(CHEMBL3110093)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195610(KDM inhibitor, 3)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446517(CHEMBL3110092)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446528(CHEMBL3110081)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446528(CHEMBL3110081)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446516(CHEMBL3110093)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446514(CHEMBL3110076)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446518(CHEMBL3110091)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446535(CHEMBL3110098)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 77nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetAcetyl-CoA carboxylase 2(Mus musculus)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446514(CHEMBL3110076)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of mouse ACC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446512(CHEMBL3110095)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446512(CHEMBL3110095)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446511(CHEMBL3110096)copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446520(CHEMBL3110089)copy SMILEScopy InChI
Affinity DataIC50: 159nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446530(CHEMBL3110079)copy SMILEScopy InChI
Affinity DataIC50: 166nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446536(CHEMBL3110097)copy SMILEScopy InChI
Affinity DataIC50: 178nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446514(CHEMBL3110076)copy SMILEScopy InChI
Affinity DataIC50: 193nMAssay Description:Inhibition of human ACC1 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446522(CHEMBL3110087)copy SMILEScopy InChI
Affinity DataIC50: 227nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446532(CHEMBL3110077)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446524(CHEMBL3110085)copy SMILEScopy InChI
Affinity DataIC50: 244nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446523(CHEMBL3110086)copy SMILEScopy InChI
Affinity DataIC50: 246nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 248nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446521(CHEMBL3110088)copy SMILEScopy InChI
Affinity DataIC50: 258nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446518(CHEMBL3110091)copy SMILEScopy InChI
Affinity DataIC50: 259nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446527(CHEMBL3110082)copy SMILEScopy InChI
Affinity DataIC50: 273nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446531(CHEMBL3110078)copy SMILEScopy InChI
Affinity DataIC50: 335nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446515(CHEMBL3110075)copy SMILEScopy InChI
Affinity DataIC50: 348nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446519(CHEMBL3110090)copy SMILEScopy InChI
Affinity DataIC50: 355nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446513(CHEMBL3110094)copy SMILEScopy InChI
Affinity DataIC50: 359nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446517(CHEMBL3110092)copy SMILEScopy InChI
Affinity DataIC50: 386nMAssay Description:Inhibition of human ACC1 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446511(CHEMBL3110096)copy SMILEScopy InChI
Affinity DataIC50: 391nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 397nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetAcetyl-CoA carboxylase 1(Mus musculus)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446514(CHEMBL3110076)copy SMILEScopy InChI
Affinity DataIC50: 427nMAssay Description:Inhibition of mouse ACC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446529(CHEMBL3110080)copy SMILEScopy InChI
Affinity DataIC50: 486nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446530(CHEMBL3110079)copy SMILEScopy InChI
Affinity DataIC50: 492nMAssay Description:Inhibition of human ACC1 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetLysine-specific demethylase 4C [1-350](Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195610(KDM inhibitor, 3)copy SMILEScopy InChI
Affinity DataIC50: 620nMpH: 7.5Assay Description:High-throughput MS assays were carried out using truncated KDM4C in 384-well V-bottom polypropylene plates (Greiner, Inc.). His-tagged recombinant KD...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446524(CHEMBL3110085)copy SMILEScopy InChI
Affinity DataIC50: 688nMAssay Description:Inhibition of human ACC1 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446516(CHEMBL3110093)copy SMILEScopy InChI
Affinity DataIC50: 724nMAssay Description:Inhibition of human ACC1 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446526(CHEMBL3110083)copy SMILEScopy InChI
Affinity DataIC50: 789nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446515(CHEMBL3110075)copy SMILEScopy InChI
Affinity DataIC50: 811nMAssay Description:Inhibition of human ACC1 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50446513(CHEMBL3110094)copy SMILEScopy InChI
Affinity DataIC50: 841nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K5KPubMed
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