Compile Data Set for Download or QSAR
Found 124 with Last Name = 'buxton' and Initial = 'j'
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Bayer Pharmaceuticals Corporation

Curated by ChEMBL
LigandPNGBDBM50200209(CHEMBL219499)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]PACAP27 from human PAC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD708RPubMed
TargetVasoactive intestinal polypeptide receptor 1(Homo sapiens (Human))
Bayer Pharmaceuticals Corporation

Curated by ChEMBL
LigandPNGBDBM50200209(CHEMBL219499)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]PACAP27 from human VPAC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD708RPubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Bayer Pharmaceuticals Corporation

Curated by ChEMBL
LigandPNGBDBM50200209(CHEMBL219499)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]PACAP27 from human VPAC2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD708RPubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Bayer Pharmaceuticals Corporation

Curated by ChEMBL
LigandPNGBDBM50200210(Ac-HSDAVFTDQYTRLRKQVAAKKYLQSIKQKRYC | CHEMBL440082)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]PACAP27 from human VPAC2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD708RPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25R3PubMed
TargetBile acid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR assessed as binding of receptor to cofactor by TRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25R3PubMed
TargetBile acid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human FXR assessed as ligand dependent binding of cofactor to the receptor-ligand complex by TRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25R3PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25R3PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25R3PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25R3PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25R3PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP25R3PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429145(CHEMBL2336215)copy SMILEScopy InChI
Affinity DataEC50:  3.83E+3nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429146(CHEMBL2336214)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429147(CHEMBL2336213)copy SMILEScopy InChI
Affinity DataEC50:  549nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429148(CHEMBL2336212)copy SMILEScopy InChI
Affinity DataEC50:  3.18E+3nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429137(CHEMBL2336223)copy SMILEScopy InChI
Affinity DataEC50:  231nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429149(CHEMBL2336210)copy SMILEScopy InChI
Affinity DataEC50:  1.46E+3nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429150(CHEMBL2336209)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429151(CHEMBL2336208)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429120(CHEMBL2336239)copy SMILEScopy InChI
Affinity DataEC50:  120nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429121(CHEMBL2336238)copy SMILEScopy InChI
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)copy SMILEScopy InChI
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50414955(CHEMBL576138)copy SMILEScopy InChI
Affinity DataEC50:  23nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429122(CHEMBL2336237)copy SMILEScopy InChI
Affinity DataEC50:  18nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429123(CHEMBL2336236)copy SMILEScopy InChI
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429124(CHEMBL2336235)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429125(CHEMBL2336234)copy SMILEScopy InChI
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429126(CHEMBL2336233)copy SMILEScopy InChI
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429127(CHEMBL2331604)copy SMILEScopy InChI
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429128(CHEMBL2336232)copy SMILEScopy InChI
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429129(CHEMBL2336231)copy SMILEScopy InChI
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429130(CHEMBL2336230)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429131(CHEMBL2336229)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429132(CHEMBL2336228)copy SMILEScopy InChI
Affinity DataEC50:  6.40E+3nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429133(CHEMBL2336227)copy SMILEScopy InChI
Affinity DataEC50:  393nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429134(CHEMBL2336226)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429135(CHEMBL2336225)copy SMILEScopy InChI
Affinity DataEC50:  3.14E+3nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429136(CHEMBL2336224)copy SMILEScopy InChI
Affinity DataEC50:  9.53E+3nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429137(CHEMBL2336223)copy SMILEScopy InChI
Affinity DataEC50:  4.68E+3nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429138(CHEMBL2336222)copy SMILEScopy InChI
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429139(CHEMBL2336221)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429140(CHEMBL2336220)copy SMILEScopy InChI
Affinity DataEC50:  920nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429141(CHEMBL2336219)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429142(CHEMBL2336218)copy SMILEScopy InChI
Affinity DataEC50:  4.93E+3nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429143(CHEMBL2336217)copy SMILEScopy InChI
Affinity DataEC50:  2.91E+3nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429144(CHEMBL2336216)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429145(CHEMBL2336215)copy SMILEScopy InChI
Affinity DataEC50:  113nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429146(CHEMBL2336214)copy SMILEScopy InChI
Affinity DataEC50:  1.48E+3nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50429147(CHEMBL2336213)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ054SPubMed
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