Compile Data Set for Download or QSAR
Found 358 with Last Name = 'chiba' and Initial = 'j'
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17909(4-{[(2S,4S)-1-[2-(3-chloro-4-{[(2-methylphenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM17909(4-{[(2S,4S)-1-[2-(3-chloro-4-{[(2-methylphenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4H7HPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM17909(4-{[(2S,4S)-1-[2-(3-chloro-4-{[(2-methylphenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:Inhibition of europium labeled human VCAM1/Fc chimera binding to human VLA-4 alpha-4-beta-1 expressed in Chinese hamster 4B4 cells by fluorimetric as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3MFVPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50423675(CHEMBL567396)copy SMILEScopy InChI
Affinity DataIC50: 0.530nMAssay Description:Inhibition of europium labeled human VCAM1/Fc chimera binding to human VLA-4 alpha-4-beta-1 expressed in Chinese hamster 4B4 cells by fluorimetric as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3MFVPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17910(4-{[(2S,4S)-1-[2-(3-bromo-4-{[(2-methylphenyl)carb...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17900(4-{[(2S,4S)-1-[2-(4-{[(2-chlorophenyl)carbamoyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 0.870nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17922(2-(1-{[(2S,4R)-4-(benzyloxy)-1-[2-(3-methoxy-4-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17930(2-(4-{[(2S,3S)-3-hydroxy-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17937(2-(4-{[(2S)-1-[2-(3-methoxy-4-{[(2-methylphenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17931(2-(4-{[(2S,4S)-4-fluoro-1-[2-(3-methoxy-4-{[(2-met...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17924(2-(1-{[(2S,4R)-4-hydroxy-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17920(2-(1-{[(2S,4R)-4-methoxy-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50428682(CHEMBL2332705)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M7XPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17934(2-(4-{[(2S,4S)-4-chloro-1-[2-(3-methoxy-4-{[(2-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17899(4-{[(2S,4S)-4-fluoro-1-[2-(3-methoxy-4-{[(2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50428687(CHEMBL2332700)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M7XPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17927(2-(4-{[(2S,4S)-1-[2-(3-methoxy-4-{[(2-methylphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17913(4-{[(2S,4S)-1-[2-(3-bromo-4-{[(2-chlorophenyl)carb...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17912(4-{[(2S,4S)-1-[2-(3-chloro-4-{[(2-chlorophenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17929(2-(4-{[(2S,3S)-3-(benzyloxy)-1-[2-(3-methoxy-4-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50157050(CHEMBL361914 | [4-(1-{2-[3-Methoxy-4-(3-o-tolyl-ur...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of VLA-4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F7QPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17933(2-(4-{[(2S)-4,4-difluoro-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17928(2-(4-{[(2S,4S)-1-[2-(3-methoxy-4-{[(2-methylphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17926(2-(4-{[(2S,3R,4S)-3,4-dihydroxy-1-[2-(3-methoxy-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17916(4-{[(2S,4S)-1-[2-(3-bromo-4-{[(2-bromophenyl)carba...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17935(2-[4-({2-[2-(3-methoxy-4-{[(2-methylphenyl)carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17925(2-(4-{[(3aR,4S,6aS)-5-[2-(3-methoxy-4-{[(2-methylp...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50273492(4-[1-[3-Chloro-4-[N'-(5-fluoro-2-methylphenyl)urei...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4H7HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17901(4-{[(2S,4S)-1-[2-(4-{[(2-bromophenyl)carbamoyl]ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50157041(CHEMBL185571 | [4-(1-{2-[3-Methoxy-4-(3-o-tolyl-ur...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of VLA-4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F7QPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17918(2-(4-{[(2S)-1-[2-(3-methoxy-4-{[(2-methylphenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50157039(CHEMBL179780 | [4-(1-{2-[3-Methoxy-4-(3-o-tolyl-ur...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of VLA-4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F7QPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17921(2-(4-{[(2S,4R)-4-(benzyloxy)-1-[2-(3-methoxy-4-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17915(4-{[(2S,4S)-1-[2-(4-{[(2-bromophenyl)carbamoyl]ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50428678(CHEMBL2332692)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M7XPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50428680(CHEMBL2332690)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M7XPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50428679(CHEMBL2332691)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M7XPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50428689(CHEMBL2332698)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M7XPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50428681(CHEMBL2332706)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M7XPubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50273911(4-[1-[3-Chloro-6-fluoro-4-[N'-(2-methylphenyl)urei...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4H7HPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50423681(CHEMBL583324)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of europium labeled human VCAM1/Fc chimera binding to human VLA-4 alpha-4-beta-1 expressed in Chinese hamster 4B4 cells by fluorimetric as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3MFVPubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50273912(4-[1-[5-chloro-4-[N'-(2-methylphenyl)ureido]-2-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4H7HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17919(2-(4-{[(2S,4R)-4-methoxy-1-[2-(3-methoxy-4-{[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50428688(CHEMBL2332699)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1M7XPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17932(2-(4-{[(2S,4R)-4-fluoro-1-[2-(3-methoxy-4-{[(2-met...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J5HPubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50273910(4-[1-[2,5-Dichloro-4-[N'-(2-methylphenyl)ureido]ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Displacement of europium labeled human VCAM1 from human VLA4 expressed in 4B4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4H7HPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17905(4-{[(2S,4S)-4-fluoro-1-[2-(3-methyl-4-{[(2-methylp...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21NSPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50423847(CHEMBL1940750)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Displacement of Eu-labeled VCAM-1 from human VLA alpha4 beta1 expressed in CHO-K1 cells after 60 mins by time-resolved fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SFKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50423857(CHEMBL1940761)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Displacement of Eu-labeled VCAM-1 from human VLA alpha4 beta1 expressed in CHO-K1 cells after 60 mins by time-resolved fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SFKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50423863(CHEMBL1940902)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Displacement of Eu-labeled VCAM-1 from human VLA alpha4 beta1 expressed in CHO-K1 cells after 60 mins by time-resolved fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SFKPubMed
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