Compile Data Set for Download or QSAR
Found 292 with Last Name = 'clayton' and Initial = 'j'
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063687(CHEMBL3397339)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063689(CHEMBL3397337)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063755(CHEMBL3397341)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063688(CHEMBL3397338)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063686(CHEMBL3397340)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063690(CHEMBL3397336)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063754(CHEMBL3397342)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063689(CHEMBL3397337)copy SMILEScopy InChI
Affinity DataKi:  0.350nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063687(CHEMBL3397339)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063691(CHEMBL3397335)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063755(CHEMBL3397341)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataKi:  0.540nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063751(CHEMBL3397344)copy SMILEScopy InChI
Affinity DataKi:  0.640nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063693(CHEMBL3397333)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063750(CHEMBL3397345)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063692(CHEMBL3397334)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063690(CHEMBL3397336)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063688(CHEMBL3397338)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063686(CHEMBL3397340)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063695(CHEMBL3397346)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063691(CHEMBL3397335)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063694(CHEMBL3397347)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063754(CHEMBL3397342)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063693(CHEMBL3397333)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063692(CHEMBL3397334)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063751(CHEMBL3397344)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063750(CHEMBL3397345)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063695(CHEMBL3397346)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063694(CHEMBL3397347)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50474994(Bisarylmaleimide 1)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration to inhibit Ser396 phosphorylation of tau, a natural substrate of GSK-3 in SY5Y cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150699(3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475025(CHEMBL181339)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475007(Bisarylmaleimide 2)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475024(CHEMBL181371)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475018(CHEMBL181518)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150699(3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475031(CHEMBL359871)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475029(CHEMBL180779)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475008(CHEMBL369090)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150698(3-(imidazo[1,2-a]pyridin-3-yl)-4-(2-(morpholine-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150700(7-(4-Imidazo[1,2-a]pyridin-3-yl-2,5-dioxo-2,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150698(3-(imidazo[1,2-a]pyridin-3-yl)-4-(2-(morpholine-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)copy SMILEScopy InChI
Affinity DataIC50: 1.49nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475022(CHEMBL361765)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150702(3-Imidazo[1,2-a]pyridin-3-yl-4-[2-(piperidine-1-ca...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150701(7-(4-(H-imidazo[1,2-a]pyridin-3-yl)-2,5-dioxo-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50474994(Bisarylmaleimide 1)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150702(3-Imidazo[1,2-a]pyridin-3-yl-4-[2-(piperidine-1-ca...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration to inhibit Ser396 phosphorylation of tau, a natural substrate of GSK-3 in SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JJGPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50150701(7-(4-(H-imidazo[1,2-a]pyridin-3-yl)-2,5-dioxo-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KG1PubMed
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