Compile Data Set for Download or QSAR
Found 48 with Last Name = 'dipaolo' and Initial = 'j'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111939(US8618107, 105)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant human full length His-tagged BTK expressed in baculovirus expression system by Z-LYTE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111938(US8618107, 104)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111939(US8618107, 105)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254236(CHEMBL4090189)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111951(US8618107, 197)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254270(CHEMBL4080943)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254277(CHEMBL4067714)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254268(CHEMBL4077625)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111998(US8618107, 312)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111945(US8618107, 113)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full length His-tagged BTK expressed in baculovirus expression system by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254278(CHEMBL4069030)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111952(US8618107, 210)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254269(CHEMBL4096404)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111998(US8618107, 312)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111943(US8618107, 109)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254279(CHEMBL4060453)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111952(US8618107, 210)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254271(CHEMBL4102294)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111951(US8618107, 197)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254270(CHEMBL4080943)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111951(US8618107, 197)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111952(US8618107, 210)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254286(CHEMBL4084331)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111945(US8618107, 113)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254273(CHEMBL4085292)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254236(CHEMBL4090189)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111939(US8618107, 105)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254279(CHEMBL4060453)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254234(CHEMBL4071845)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111939(US8618107, 105)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111938(US8618107, 104)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111998(US8618107, 312)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111945(US8618107, 113)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254279(CHEMBL4060453)copy SMILEScopy InChI
Affinity DataIC50: 137nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254237(CHEMBL4095477)copy SMILEScopy InChI
Affinity DataIC50: 139nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254278(CHEMBL4069030)copy SMILEScopy InChI
Affinity DataIC50: 171nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254277(CHEMBL4067714)copy SMILEScopy InChI
Affinity DataIC50: 193nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111943(US8618107, 109)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254269(CHEMBL4096404)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254234(CHEMBL4071845)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254286(CHEMBL4084331)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254268(CHEMBL4077625)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254235(CHEMBL4100365)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254272(CHEMBL4082346)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human whole blood assessed as suppression of BCR-induced CD69 expression on B cells prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254235(CHEMBL4100365)copy SMILEScopy InChI
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM50254272(CHEMBL4082346)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96ZHPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111939(US8618107, 105)copy SMILEScopy InChI
Affinity DataEC50:  22nMAssay Description:Inhibition of BTK in human B-cells assessed as decrease in BCR-stimulated B-cell proliferation after 8 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech, Inc., Research and Early Development, 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL
LigandPNGBDBM111939(US8618107, 105)copy SMILEScopy InChI
Affinity DataEC50:  33nMAssay Description:Inhibition of BTK in human monocytes assessed as inhibition of FCgammaR activation-induced TNFalpha production by ELISAMore data for this Ligand-Target Pair