Compile Data Set for Download or QSAR
Found 42 with Last Name = 'el yazal' and Initial = 'j'
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8964(CHEMBL75274 | Homodimeric Tacrine Analog 3c | N-[8...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9441(CHEMBL1082738 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9440(CHEMBL1084775 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 10.1nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9435(CHEMBL1084369 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 12.8nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9436(CHEMBL1084096 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 13.6nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9442(CHEMBL1082739 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 38.7nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9433(CHEMBL1084367 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9431(CHEMBL1084094 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9430(CHEMBL1083791 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 52nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9432(CHEMBL1084095 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 71nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9437(CHEMBL1084530 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 83.6nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9426(CHEMBL258928 | Heterodimeric Tacrine-Based Inhibit...)copy SMILEScopy InChI
Affinity DataIC50: 89.4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8964(CHEMBL75274 | Homodimeric Tacrine Analog 3c | N-[8...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9440(CHEMBL1084775 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9441(CHEMBL1082738 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9427(CHEMBL1083790 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 131nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9430(CHEMBL1083791 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 143nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9428(CHEMBL1084092 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 147nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)copy SMILEScopy InChI
Affinity DataIC50: 149nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9442(CHEMBL1082739 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9436(CHEMBL1084096 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 157nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9431(CHEMBL1084094 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9438(CHEMBL1084531 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 176nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9429(CHEMBL1084093 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9437(CHEMBL1084530 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9426(CHEMBL258928 | Heterodimeric Tacrine-Based Inhibit...)copy SMILEScopy InChI
Affinity DataIC50: 202nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 223nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9432(CHEMBL1084095 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 237nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9439(Heterodimeric Tacrine-Based Inhibitor 7k | N-4-Pyr...)copy SMILEScopy InChI
Affinity DataIC50: 261nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9434(CHEMBL1084368 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 264nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9435(CHEMBL1084369 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 302nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9425(CHEMBL1083789 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 319nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9425(CHEMBL1083789 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 357nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9439(Heterodimeric Tacrine-Based Inhibitor 7k | N-4-Pyr...)copy SMILEScopy InChI
Affinity DataIC50: 377nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9438(CHEMBL1084531 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 427nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9433(CHEMBL1084367 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 581nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9428(CHEMBL1084092 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 682nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9427(CHEMBL1083790 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 687nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9434(CHEMBL1084368 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 695nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9429(CHEMBL1084093 | Heterodimeric Tacrine-Based Inhibi...)copy SMILEScopy InChI
Affinity DataIC50: 791nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957CHPubMed