Compile Data Set for Download or QSAR
Found 829 with Last Name = 'feutrill' and Initial = 'j'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134434(CHEMBL3746046)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134433(CHEMBL3745968)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134429(CHEMBL3746964)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134432(CHEMBL3747036)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134428(CHEMBL3746007)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313807(US10167292, Example 51B)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311010(CHEMBL1078889 | N-(4-{2-[4-(1,1-Dioxo-1lambda*6*-t...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313798(US10167292, Example 42)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313791(US10167292, Example 35)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311001(2-methoxy-4-(2-(4-morpholinophenylamino)pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313807(US10167292, Example 51B)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50539625(CHEMBL4640664)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q7SPubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50539626(CHEMBL4642708)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q7SPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311011(CHEMBL1079077 | N-(4-(2-(4-morpholinophenylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313789(US10167292, Example 33)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134393(CHEMBL3746464)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50539636(CHEMBL4641234)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q7SPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134430(CHEMBL3747248)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134434(CHEMBL3746046)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50539627(CHEMBL4646285)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q7SPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313798(US10167292, Example 42)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313791(US10167292, Example 35)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311012(CHEMBL1079078 | N-(4-(2-(4-(4-hydroxypiperidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313807(US10167292, Example 51B)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134431(CHEMBL3747181)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311002(CHEMBL1078275 | N-(4-(2-(3-(pyrrolidin-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313774(US10167292, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM86612(Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, 1...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q7SPubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50539635(CHEMBL4645836)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q7SPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313773(US10167292, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313797(US10167292, Example 41)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313807(US10167292, Example 51B)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313775(US10167292, Example 10)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134391(CHEMBL3747090)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134394(CHEMBL3747325)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313779(US10167292, Example 16)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134433(CHEMBL3745968)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D4MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311022(CHEMBL1078005 | N-(cyanomethyl)-4-(5-methyl-2-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311004(CHEMBL1078277 | N-(4-(2-(3-(morpholinomethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313774(US10167292, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311019(CHEMBL1078364 | N-(cyanomethyl)-2-methoxy-4-(2-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311006(CHEMBL1078689 | N-(4-(2-(4-(morpholinomethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313796(US10167292, Example 40)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311016(2-cyano-N-(4-(2-(4-morpholinophenylamino)pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WKMPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313791(US10167292, Example 35)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313773(US10167292, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313775(US10167292, Example 10)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50539628(CHEMBL4648763)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8Q7SPubMed
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