Compile Data Set for Download or QSAR
Found 245 with Last Name = 'fujimoto' and Initial = 'j'
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50245999(CHEMBL4084502)copy SMILEScopy InChI
Affinity DataIC50: 0.520nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241875(CHEMBL4091527)copy SMILEScopy InChI
Affinity DataIC50: 0.540nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50245999(CHEMBL4084502)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50245998(CHEMBL4064555)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50245998(CHEMBL4064555)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241879(CHEMBL4082587)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241892(CHEMBL4072106)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241862(CHEMBL4059523)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241864(CHEMBL4069244)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246049(CHEMBL4102458)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246049(CHEMBL4102458)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246023(CHEMBL4060775)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241882(CHEMBL4101552)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241863(CHEMBL4060561)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241896(CHEMBL4081088)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246000(CHEMBL4070383)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246000(CHEMBL4070383)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241890(CHEMBL4098004)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241858(CHEMBL4070459)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241881(CHEMBL4063489)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241868(CHEMBL4092865)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241885(CHEMBL4060759)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241866(CHEMBL4063709)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241860(CHEMBL4079977)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241857(CHEMBL4091382)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241891(CHEMBL4082444)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241868(CHEMBL4092865)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of kinase tracer 236 binding to GST-tagged CDK19/CycC (unknown origin) after 60 min by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241871(CHEMBL4087219)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241874(CHEMBL4079336)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50024849(CHEMBL3337825)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Displacement of [3H]aldosterone from human mineralocorticoid receptor expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218383GPubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246023(CHEMBL4060775)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246000(CHEMBL4070383)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246000(CHEMBL4070383)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241859(CHEMBL4063908)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50024859(CHEMBL3337831)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]aldosterone from human mineralocorticoid receptor expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218383GPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241861(CHEMBL4087859)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246076(CHEMBL4063561)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246045(CHEMBL4090490)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241866(CHEMBL4063709)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of kinase tracer 236 binding to GST-tagged CDK19/CycC (unknown origin) after 60 min by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241900(CHEMBL4066959)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50024859(CHEMBL3337831)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in COS1 cells after 1 day by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218383GPubMed
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246045(CHEMBL4090490)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of D5D in human HepG2 cells assessed as [14C]AA formation from [14C]DGLA preincubated for 30 mins followed by [14C]eicosatrienoic acid add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241897(CHEMBL4061835)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50024847(CHEMBL3337823)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]aldosterone from human mineralocorticoid receptor expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218383GPubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50246007(CHEMBL4104260)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25S7PubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241870(CHEMBL4094902)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241899(CHEMBL4085116)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241872(CHEMBL4097361)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241869(CHEMBL4093832)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50024849(CHEMBL3337825)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in COS1 cells after 1 day by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218383GPubMed
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