TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of JNK3 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of JNK3 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 23nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 55nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 60nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of JNK3 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of JNK3 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 80nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of JNK3 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 110nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 113nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of JNK3 by HTRF assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Inhibition of JNK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 133nMAssay Description:Inhibition of JNK3 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of JNK3 by HTRF assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of JNK3 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 148nMAssay Description:Inhibition of JNK3 by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of JNK3 by HTRF assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q26M36KXPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q26M36KXPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 170nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 200nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of JNK3 by HTRF assayMore data for this Ligand-Target Pair
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 210nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of JNK3 by HTRF assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of JNK3 by HTRF assayMore data for this Ligand-Target Pair
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 250nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of JNK3 by HTRF assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
and Translational Research Institute
Curated by ChEMBL
and Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair